Genomic Insights into Methicillin-Resistant Staphylococcus aureus spa Type t899 Isolates Belonging to Different Sequence Types
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F21%3AN0000031" target="_blank" >RIV/00027162:_____/21:N0000031 - isvavai.cz</a>
Alternative codes found
RIV/62157124:16270/21:43879685
Result on the web
<a href="https://aem.asm.org/content/87/6/e01994-20/article-info" target="_blank" >https://aem.asm.org/content/87/6/e01994-20/article-info</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1128/AEM.01994-20" target="_blank" >10.1128/AEM.01994-20</a>
Alternative languages
Result language
angličtina
Original language name
Genomic Insights into Methicillin-Resistant Staphylococcus aureus spa Type t899 Isolates Belonging to Different Sequence Types
Original language description
Methicillin-resistant Staphylococcus aureus (MRSA) presenting spa type t899 is commonly associated with sequence type 9 (ST9) but is also increasingly linked to ST398. This study provides genomic insight into the diversity of t899 isolates using core genome multilocus sequence typing (cgMLST), single nucleotide polymorphism (SNP)-based phylogeny, and the description of selected antimicrobial resistance and virulence markers. The SNP-based phylogenic tree showed that isolates sharing the same spa type (t899) but different STs highly diverged in their core and accessory genomes, revealing discriminant antimicrobial resistance (AMR) and virulence markers. Our results highlighted the idea that in a surveillance context where only spa typing is used, an additional multiplex PCR for the detection of the tet(M), sak, and seg genes would be valuable in helping distinguish ST9 from ST398 isolates on a routine basis.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology
Result continuities
Project
<a href="/en/project/ED2.1.00%2F19.0385" target="_blank" >ED2.1.00/19.0385: Development of research capacities for AdmireVet</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
ISSN
0099-2240
e-ISSN
1098-5336
Volume of the periodical
87
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
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UT code for WoS article
000623325400005
EID of the result in the Scopus database
2-s2.0-85102050821