Development of piglet gut microbiota at the time of weaning influences development of postweaning diarrhea
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F21%3AN0000033" target="_blank" >RIV/00027162:_____/21:N0000033 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0034528820311243" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0034528820311243</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.rvsc.2020.12.022" target="_blank" >10.1016/j.rvsc.2020.12.022</a>
Alternative languages
Result language
angličtina
Original language name
Development of piglet gut microbiota at the time of weaning influences development of postweaning diarrhea
Original language description
Postweaning diarrhea is a common issue in pig production which is currently controlled by feed supplementation with zinc oxide. However, new alternatives are being sought due to an expected ban on zinc oxide in feed supplementation from 2022 in the EU. One possible alternative is to use novel types of probiotics consisting of microbiota characteristic for healthy weaned piglets. In this study, we therefore collected rectal swabs of piglets 3 days before weaning and 4 days after weaning in a commercial farm considering all risks of field trial like the use of antibiotics, classified the piglets as predisposed, healthy or sick and using 16S rRNA sequencing, we determined and compared the microbiota composition. Increased Actinobacteria before weaning was a marker of piglets predisposed for diarrhea. Increased Chlamydia or Helicobacter before weaning was surprisingly a marker of healthy and resistant piglets after weaning. After weaning, unclassified Clostridiales, Deltaproteobacteria, Selenomonadales, Fusobacterium, Akkermansia or Anaerovibrio increased in microbiota of piglets with postweaning diarrhea while an increase in Prevotella and Faecalibacterium was characteristic for healthy, weaned piglets. Both changes in individual microbiota members and also correct timing of microbiota reshaping around weaning and the increase of mainly Prevotella species just after weaning are equally important for resistance to postweaning diarrhea in piglets under field conditions.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
40301 - Veterinary science
Result continuities
Project
<a href="/en/project/QK1810462" target="_blank" >QK1810462: Manipulation of the intestinal microbiota of pigs and poultry to reduce E. coli infections and use of antimicrobials</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Research in Veterinary Science
ISSN
0034-5288
e-ISSN
1532-2661
Volume of the periodical
135
Issue of the periodical within the volume
MAR 2021
Country of publishing house
GB - UNITED KINGDOM
Number of pages
7
Pages from-to
59-65
UT code for WoS article
000632840800007
EID of the result in the Scopus database
2-s2.0-85099129112