Controlled synthesis of gemini surfactant-capped gold nanoparticles. Gemini structure-nanoparticle properties relationship study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F22%3AN0000093" target="_blank" >RIV/00027162:_____/22:N0000093 - isvavai.cz</a>

Alternative codes found

RIV/00216305:26310/22:PU146989

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S0167732222017494?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0167732222017494?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.molliq.2022.120210" target="_blank" >10.1016/j.molliq.2022.120210</a>

Result language

angličtina

Original language name

Controlled synthesis of gemini surfactant-capped gold nanoparticles. Gemini structure-nanoparticle properties relationship study

Original language description

Gold nanoparticles were prepared by the method of chemical reduction utilising sodium borohydride as reducing agent and stabilised with bisammonium gemini surfactants with variable length of poly methylene spacer. Physico-chemical investigations indicated the presence of plasmon resonance peaks in the wavelength range 507–544 nm for all investigated Au nanodispersions. The nanoparticle size anal ysis shows the relationship between the size of gold nanoparticles and the spacer length of stabilising gemini molecules. The strong aggregation tendency of gemini surfactants with short polymethylene spacer composed of 2–4 methylene units in aqueous solutions may be responsible for the formation of clusters of gold nanoparticles which results in the observed large hydrodynamic size of nanoparticle clus ters at the surfactants concentrations below the CMC. At higher surfactant-to-gold molar ratio values, clusters disintegration occurs and the decrease in size of the nanoparticles is observed. The shape of gold nanoparticles was found to be spherical and polyhedral, as evidenced by the SEM images. The size values varied between 30–60 nm and 10–15 nm for AuNPs capped with gemini molecules with short and medium/long spacer, respectively. Gold nanoparticles are strongly positively charged, with positive zeta potential values being in the interval +44 to +90 mV in the whole analysed region of molar ratio values and surfactant spacer length. The biological experiments indicate a dependence of biological activity of gold nanoparticles on the structural parameter (spacer length) of stabilising gemini molecules. Both cyto toxicity and anti-inflammatory activity of gold nanoparticles were found to increase with the increasing gemini spacer length up to 12 methylene groups in the spacer.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30107 - Medicinal chemistry

Project

<a href="/en/project/EF15_003%2F0000495" target="_blank" >EF15_003/0000495: FIT (Pharmacology, Immunotherapy, nanoToxicology)</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Molecular Liquids

ISSN

0167-7322

e-ISSN

1873-3166

Volume of the periodical

365

Issue of the periodical within the volume

1 November 2022

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

13

Pages from-to

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UT code for WoS article

000861204500008

EID of the result in the Scopus database

2-s2.0-85137167080