Determination of 19-noretiocholanolone glucuronide and 19-norandrosterone glucuronide by using liquid chromatography with tandem mass spectrometric detection in urine

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F25%3AN0000168" target="_blank" >RIV/00027162:_____/25:N0000168 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Determination of 19-noretiocholanolone glucuronide and 19-norandrosterone glucuronide by using liquid chromatography with tandem mass spectrometric detection in urine
Original language description
Conference poster: TRACES 2025 - Residues of pharmacologically active substances in food, feed and environment within the One Health concept (3-6 June 2025, Ghent, Belgium). This study describes a LC-MS/MS method which has been developed for determination of two glucuronides (19-noretiocholanolone, 19-norandrosterone) in urine. As internal standard was used 19-norandrosterone-d.The measurement of glucuronides was carried out by triplequadrupole LC-MS system. The method for determination of glucuronides in urine has been validated according to Regulation (EU)2021/808/EC. Decision limits for analytes were observed between 0.31 - 0.57 ng/ml. The method is robust for bovine and porcine urine analysesand can be applied both for screening and confirmatory determination in routine residue monitoring.
Czech name
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Czech description
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Project
<a href="/en/project/QL24010272" target="_blank" >QL24010272: Omics as a modern tool for the detection of banned growth promoters in fattening food-producing animals</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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