High frequency of Candida fabianii among clinical isolates biochemically identified as Candida pelliculosa and Candida utilis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F16%3A10323670" target="_blank" >RIV/00064165:_____/16:10323670 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/16:00090598 RIV/00216208:11130/16:10323670 RIV/00216208:11150/16:10323670 RIV/61989592:15110/16:33162642 and 4 more

Result on the web

<a href="http://dx.doi.org/10.1111/myc.12454" target="_blank" >http://dx.doi.org/10.1111/myc.12454</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/myc.12454" target="_blank" >10.1111/myc.12454</a>

Result language

angličtina

Original language name

High frequency of Candida fabianii among clinical isolates biochemically identified as Candida pelliculosa and Candida utilis

Original language description

Clinical yeast isolates belonging to Candida pelliculosa, Candida utilis and Candida fabianii are difficult to distinguish in a routine mycology laboratory using common biochemical tests. The aims of this study were to determine the prevalence of C. pelliculosa, C. utilis and C. fabianii in clinical samples and to compare their minimum inhibitory concentrations (MICs) to systemic antifungals. Two hundred and forty-eight clinical yeast isolates obtained from eight large hospitals in the Czech Republic were included in this study. Identification was performed biochemically using ID 32C kit and by MALDI-TOF MS. MICs were determined using colorimetric broth dilution Sensititre YeastOne panels. From a total number of 248 isolates, 175 were identified as C. pelliculosa and 73 as C. utilis using the biochemical kit. In contrast, MALDI-TOF MS identified 222 isolates as C. fabianii, 20 as C. pelliculosa and 6 as C. utilis. The highest mean MICs were found in C. fabianii and, regardless of the studied species, in isolates from blood cultures and central venous catheters. MALDI-TOF MS revealed C. fabianii to be most prevalent in clinical samples as compared with the other studied species. Higher MIC values in C. fabianii support the importance of correct identification of this species.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

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Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Mycoses

ISSN

0933-7407

e-ISSN

—

Volume of the periodical

59

Issue of the periodical within the volume

4

Country of publishing house

DE - GERMANY

Number of pages

6

Pages from-to

241-246

UT code for WoS article

000372295900005

EID of the result in the Scopus database

2-s2.0-84960119133