Narcolepsy with cataplexy in patients aged over 60 years: a case-control study

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F16%3A10331402" target="_blank" >RIV/00064165:_____/16:10331402 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/16:10331402 RIV/00216208:11210/16:10331402
Result on the web
<a href="http://dx.doi.org/10.1016/j.sleep.2016.05.011" target="_blank" >http://dx.doi.org/10.1016/j.sleep.2016.05.011</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.sleep.2016.05.011" target="_blank" >10.1016/j.sleep.2016.05.011</a>

Result language
angličtina
Original language name
Narcolepsy with cataplexy in patients aged over 60 years: a case-control study
Original language description
Objective: Narcolepsy with cataplexy (NC) is a chronic disabling disease; however, there are insufficient data on older NC subjects. Methods: A cross-sectional evaluation on health and social status, including intensity and progression of NC symptoms, was performed on 42 NC patients (age 71.9 years +/- 7.5) and 46 age-and-sex-matched controls (age 72.2 years +/- 7.0). Results: A greater proportion of patients than controls suffered from hypertension and type 2 diabetes. More controls had a history of treated depression; however, according to the Geriatric Depression Scale, more NC patients scored in the range of depression. There were no significant differences in Addenbrook Cognitive Examination scores. Average physical fitness assessed by the Short Physical Performance Battery was lower in the NC group. The frequency of meeting with family, friends, and participation in hobbies or sports did not differ between the two groups. Conclusions: Symptoms of NC were present throughout life. Comorbidities and lower physical fitness, which are known to be present in young and middle-aged NC subjects, were also present in older patients. Although NC subjects were less professionally active during their lifetime, they did not differ from controls in important social parameters in older age.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Project
<a href="/en/project/NT13238" target="_blank" >NT13238: Narcolepsy – clinical picture, pathophysiology, ageing, comorbidities and physical activity regimen</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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