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The molecular basis of jaundice: An old symptom revisited

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F17%3A10364164" target="_blank" >RIV/00064165:_____/17:10364164 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/17:10364164

  • Result on the web

    <a href="http://dx.doi.org/10.1111/liv.13351" target="_blank" >http://dx.doi.org/10.1111/liv.13351</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1111/liv.13351" target="_blank" >10.1111/liv.13351</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The molecular basis of jaundice: An old symptom revisited

  • Original language description

    Increased serum bilirubin level is a widely used diagnostic marker for hepatic illnesses. Nevertheless, mild elevation of unconjugated serum bilirubin (such as in Gilbert syndrome) has been recently demonstrated to correlate with low risk of chronic inflammatory and/or oxidative stress-mediated diseases. In accord, a low serum bilirubin level has emerged as an important predisposing factor or a biomarker of these pathologic conditions including cardiovascular, tumour, and possibly neurodegenerative diseases. Bilirubin possesses multiple biological actions with interaction in a complex network of enzymatic and signalling pathways. The fact that the liver is the main organ controlling the bioavailability of bilirubin emphasizes the central role of this organ in human health.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30219 - Gastroenterology and hepatology

Result continuities

  • Project

    <a href="/en/project/NV15-28895A" target="_blank" >NV15-28895A: Bilirubin as a risk factor of cardiovascular disease development.</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Liver International

  • ISSN

    1478-3223

  • e-ISSN

  • Volume of the periodical

    37

  • Issue of the periodical within the volume

    8

  • Country of publishing house

    DK - DENMARK

  • Number of pages

    9

  • Pages from-to

    1094-1102

  • UT code for WoS article

    000405575400001

  • EID of the result in the Scopus database

    2-s2.0-85023607274