Fusion of microelectrode neuronal recordings and MRI landmarks for automatic atlas fitting in deep brain stimulation surgery

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F18%3A10383220" target="_blank" >RIV/00064165:_____/18:10383220 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21230/18:00325455 RIV/00216208:11110/18:10383220
Result on the web
<a href="http://dx.doi.org/10.1007/978-3-030-01201-4_19" target="_blank" >http://dx.doi.org/10.1007/978-3-030-01201-4_19</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-030-01201-4_19" target="_blank" >10.1007/978-3-030-01201-4_19</a>

Result language
angličtina
Original language name
Fusion of microelectrode neuronal recordings and MRI landmarks for automatic atlas fitting in deep brain stimulation surgery
Original language description
The deep brain stimulation (DBS) is a symptomatic treatment technique used mainly for movement disorders, consisting of chronic electrical stimulation of subcortical structures. To achieve very precise electrode implantation, which is necessary for a good clinical outcome, many surgical teams use electrophysiological recording around the assumed target, planned in pre-operative MRI images. In our previous work, we developed a probabilistic model to fit a 3D anatomical atlas of the subthalamic nucleus to the recorded microelectrode activity in Parkinson's disease (PD) patients. In this paper, we extend the model to incorporate characteristic landmarks of the target nucleus, manually annotated in pre-operative MRI data. We validate the approach on a set of 27 exploration five-electrode trajectories from 15 PD patients. The results show that such combined approach may lead to a vast improvement in optimization reliability, while maintaining good fit to the electrophysiology data. The combination of electrophysiology and MRI-based data thus provides a promising approach for compensating brain shift, occuring during the surgery and achieving accurate localization of recording sites in DBS surgery.
Czech name
—
Czech description
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Project
<a href="/en/project/GA16-13323S" target="_blank" >GA16-13323S: MIcro and MAcro Connectomics of the Subthalamic nucleus in humans: impact of neuromodulation and dopamine depletion</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
OR 2.0 Context-Aware Operating Theaters, Computer Assisted Robotic Endoscopy, Clinical Image-Based Procedures, and Skin Image Analysis
ISBN
978-3-030-01200-7
ISSN
0302-9743
e-ISSN
neuvedeno
Number of pages
9
Pages from-to
175-183
Publisher name
Springer Verlag
Place of publication
Berlin
Event location
Granada, Spain
Event date
Sep 16, 2018
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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