Gait festination in parkinsonism: introduction of two phenotypes

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F19%3A10385497" target="_blank" >RIV/00064165:_____/19:10385497 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/19:10385497 RIV/00216208:11120/19:43917427 RIV/00064173:_____/19:N0000185
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=p3~VLMbyVm" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=p3~VLMbyVm</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00415-018-9146-7" target="_blank" >10.1007/s00415-018-9146-7</a>

Result language
angličtina
Original language name
Gait festination in parkinsonism: introduction of two phenotypes
Original language description
Gait festination is one of the most characteristic gait disturbances in patients with Parkinson's disease or atypical parkinson-ism. Although festination is common and disabling, it has received little attention in the literature, and different definitions exist. Here, we argue that there are actually two phenotypes of festination. The first phenotype entails a primary locomotion disturbance, due to the so-called sequence effect: a progressive shortening of step length, accompanied by a compensatory increase in cadence. This phenotype strongly relates to freezing of gait with alternating trembling of the leg. The second phenotype results from a postural control problem (forward leaning of the trunk) combined with a balance control deficit (inappropriately small balance-correcting steps). In this viewpoint, we elaborate on the possible pathophysiological substrate of these two phenotypes of festination and discuss their management in daily clinical practice.
Czech name
—
Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30103 - Neurosciences (including psychophysiology)

Project
<a href="/en/project/NV16-28119A" target="_blank" >NV16-28119A: Analysis of movement disorders for the study of extrapyramidal diseases mechanisms using motion capture camera systems</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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