Inpatient multidisciplinary rehabilitation programme for postural and gait stability in Huntington's disease a pilot study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F19%3A10395575" target="_blank" >RIV/00064165:_____/19:10395575 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21230/19:00332140 RIV/00216208:11110/19:10395575
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=5pbJiTs0lr" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=5pbJiTs0lr</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.14735/amcsnn2019301" target="_blank" >10.14735/amcsnn2019301</a>
Alternative languages
Result language
angličtina
Original language name
Inpatient multidisciplinary rehabilitation programme for postural and gait stability in Huntington's disease a pilot study
Original language description
Aim: Postural and gait instability in Huntington's disease (HD) is a key component of the motor symptomatology which contributes to an increased risk of falls. Rehabilitation is considered beneficial in postural and gait stability treatment. We aimed to explore the feasibility and the short-and long-term effects of an inpatient multidisciplinary rehabilitation program on postural and gait stability in subjects with HD. Methods: A sample of 13 subjects with HD but with no severe cognitive deficit or depression underwent a 3-week specific inpatient rehabilitation program focused on postural and gait stability. Patients were examined at the baseline, after the completion of rehabilitation, and then 1 month and 3 months after the end of the program. The testing included: gait stability examination (Dynamic Gait Index; DGI), posturography examination of postural stability on a stable (PSS) and 20% unstable (PSU) platform and the total motor score evaluation by Unified Huntington's Disease Rating Scale (UHDRS). Results: There was a significant improvement lasting 3 months in PSS and a significant improvement in DGI immediately after the rehabilitation. There was no significant improvement in the PSU and UHDRS total motor score. Conclusion: Specific rehabilitation methods are safe and feasible and may be beneficial in the treatment of postural and gait instability in patients with early and mid-stage HD. The postural instability improvement measured by PSS persisted for at least 3 months. The gait stability improvement in DGI did not persist after 1 month. We found no improvement in PSU. This exploratory study offers a sample of a specific rehabilitation protocol for stability training in HD.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
<a href="/en/project/NV17-32318A" target="_blank" >NV17-32318A: Influence of Rehabilitation on Gait and Balance Disorders in Neurodegenerative Diseases Affecting Basal Ganglia</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Česká a slovenská neurologie a neurochirurgie
ISSN
1210-7859
e-ISSN
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Volume of the periodical
82
Issue of the periodical within the volume
3
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
8
Pages from-to
301-308
UT code for WoS article
000472881100011
EID of the result in the Scopus database
2-s2.0-85068688363