ASXL1 gene alterations in patients with isolated 20q deletion
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F19%3A10400933" target="_blank" >RIV/00064165:_____/19:10400933 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/19:10400933 RIV/00023736:_____/19:00012515
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Ekc7ubOUJa" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Ekc7ubOUJa</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.4149/neo_2018_181010N754" target="_blank" >10.4149/neo_2018_181010N754</a>
Alternative languages
Result language
angličtina
Original language name
ASXL1 gene alterations in patients with isolated 20q deletion
Original language description
Deletion 20q is a recurrent abnormality in myeloid malignancies. In our previous study, we identified fusion of additional sex combs-like 1 (ASXL1) and teashirt zinc finger homeobox 2 genes in a patient with myelodysplastic syndrome. The objective of this study was to determine the frequency of ASXL1 breakpoints in a cohort of 36 patients with deletion 20q as the sole cytogenetic aberration. A combination of molecular cytogenetic methods was used to confirm ASXL1 gene alterations in 19 of the 36 patients and the determination of ASXL1 gene changes in patients with deletion 20q revealed clinical and prognostic impacts.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10600 - Biological sciences
Result continuities
Project
<a href="/en/project/GBP302%2F12%2FG157" target="_blank" >GBP302/12/G157: Dynamics and Organization of Chromosomes in the Cell Cycle and during Differentiation under Normal and Pathological Conditions</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neoplasma
ISSN
0028-2685
e-ISSN
—
Volume of the periodical
66
Issue of the periodical within the volume
4
Country of publishing house
SK - SLOVAKIA
Number of pages
4
Pages from-to
627-630
UT code for WoS article
000491238200014
EID of the result in the Scopus database
2-s2.0-85062832906