Efficacy of unithiol (2,3-dimercaptopropanesulfonate) and acetylcysteine in a patient with arthroplastic cobalt toxicity
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F23%3A10464313" target="_blank" >RIV/00064165:_____/23:10464313 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/23:10464313
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=1F3MSrPVmc" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=1F3MSrPVmc</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/15563650.2023.2178934" target="_blank" >10.1080/15563650.2023.2178934</a>
Alternative languages
Result language
angličtina
Original language name
Efficacy of unithiol (2,3-dimercaptopropanesulfonate) and acetylcysteine in a patient with arthroplastic cobalt toxicity
Original language description
Previously we reported a 56-year-old man with severe cobalt poisoning from a damaged metal-on-ceramic hip prosthesis. He was treated with a total of 10 g of oral unithiol (2,3-dimercaptopropanesulfonate; DMPS) over 15 days beginning 2.5 weeks after his prosthesis was removed. His urinary cobalt concentration increased from 137 µg/L to 305 µg/L and his serum cobalt concentration decreased from 506 µg/L to 130 µg/L over four weeks, during which time his symptoms almost completely resolved. Based on this experience we treated two more patients who are reported herein.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30104 - Pharmacology and pharmacy
Result continuities
Project
—
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Clinical Toxicology
ISSN
1556-3650
e-ISSN
1556-9519
Volume of the periodical
61
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
2
Pages from-to
201-202
UT code for WoS article
000938197900001
EID of the result in the Scopus database
2-s2.0-85148647830