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A Review Article on Exercise Intolerance in Long COVID: Unmasking the Causes and Optimizing Treatment Strategies

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F23%3A10471037" target="_blank" >RIV/00064165:_____/23:10471037 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/23:10471037

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=oFZTEslPl5" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=oFZTEslPl5</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.12659/MSM.941079" target="_blank" >10.12659/MSM.941079</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    A Review Article on Exercise Intolerance in Long COVID: Unmasking the Causes and Optimizing Treatment Strategies

  • Original language description

    There is a growing body of research on SARS-CoV-2 (PASC), previously known as the post-COVID syndrome, a chronic condition characterized by symptoms that persist after SARS-CoV-2 infection. Among these symptoms, feelings of physical exhaustion and prolonged fatigue are particularly prevalent and can significantly impact patients&apos; quality of life. These symptoms are associated with reduced overall physical capacity, decreased daily physical activity, malaise after intense training, and intolerance to physical activity (IFA). IFA, described as a reduced ability to perform physical activities typical for the patient&apos;s age, can often lead to a sedentary lifestyle. Prolonged physical inactivity can cause deterioration in the overall physical condition and disrupt mitochondrial function, triggering a vicious cycle of gradual symptom worsening.The underlying causes of PASC remain unclear; however, several biochemical mechanisms have been discussed to explain the body&apos;s energy depletion, and a multidisciplinary approach that combines physical and cognitive rehabilitation and lifestyle interventions such as exercise and diet modifications has been suggested to improve the overall health and well-being of PASC patients.This critical review aims to review the existing research on the possible causes and links among chronic fatigue, reduced physical activity, and exercise intolerance in patients with PASC. Further research into the underlying causes and treatment of PASC and the importance of developing individualized treatment is needed to address each patient&apos;s unique health requirements.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30300 - Health sciences

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Medical Science Monitor

  • ISSN

    1234-1010

  • e-ISSN

    1643-3750

  • Volume of the periodical

    29

  • Issue of the periodical within the volume

    October

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    9

  • Pages from-to

    e941079

  • UT code for WoS article

    001092029500001

  • EID of the result in the Scopus database

    2-s2.0-85175274940