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Heart rhythm at hospital admission: A factor for survival and neurological outcome among ECPR recipients?

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F24%3A10488698" target="_blank" >RIV/00064165:_____/24:10488698 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/24:10488698 RIV/00216208:11320/24:10488698

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=KCv7P3Vylf" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=KCv7P3Vylf</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.resuscitation.2024.110412" target="_blank" >10.1016/j.resuscitation.2024.110412</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Heart rhythm at hospital admission: A factor for survival and neurological outcome among ECPR recipients?

  • Original language description

    Background: The initial rhythm is a known predictor of survival in extracorporeal cardiopulmonary resuscitation (ECPR) patients. However, the effect of the rhythm at hospital admission on outcomes in these patients is less clear. Methods: This observational, single-center study assessed the influence of the rhythm at hospital admission on 30day survival and neurological outcomes at discharge in patients who underwent ECPR for out-of-hospital cardiac arrest (OHCA). Results: Between January 2012 and December 2023, 1,219 OHCA patients were admitted, and 210 received ECPR. Of these, 196 patients were analyzed. The average age was 52.9 years (+/- 13), with 80.6 % male. The median time to ECPR initiation was 61 min (IQR 54-72). Patients with ventricular fibrillation as both the initial and admission rhythm had the highest 30-day survival rate (52 %: 35/67), while those with asystole in both instances had the lowest (6 %: 1/17, log-rank p &lt; 0.00001). After adjusting for age, sex, initial rhythm, resuscitation time, location, bystander, and witnessed status, asystole at admission was linked to higher 30-day mortality (OR 4.03, 95 % CI 1.49-12.38, p = 0.009) and worse neurological outcomes (Cerebral Performance Category 3-5) at discharge (OR 4.61, 95 % CI 1.49-17.62, p = 0.013). Conclusions: The rhythm at hospital admission affects ECPR outcomes. Patients presenting with and maintaining ventricular fibrillation have a higher chance of favorable neurological survival, whereas those presenting with or converting to asystole have poor outcomes. The rhythm at hospital admission appears to be a valuable criterion for deciding on ECPR initiation.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30201 - Cardiac and Cardiovascular systems

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Resuscitation

  • ISSN

    0300-9572

  • e-ISSN

    1873-1570

  • Volume of the periodical

    204

  • Issue of the periodical within the volume

    November

  • Country of publishing house

    IE - IRELAND

  • Number of pages

    5

  • Pages from-to

    110412

  • UT code for WoS article

    001343374400001

  • EID of the result in the Scopus database

    2-s2.0-85206908907