Porphyria cutanea tarda triggered by hepatitis-E virus
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F24%3A10488867" target="_blank" >RIV/00064165:_____/24:10488867 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/24:10488867
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=m9Ol-L~Jc3" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=m9Ol-L~Jc3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.4149/BLL_2024_91" target="_blank" >10.4149/BLL_2024_91</a>
Alternative languages
Result language
angličtina
Original language name
Porphyria cutanea tarda triggered by hepatitis-E virus
Original language description
Porphyria cutanea tarda (PCT) is the most common chronic porphyria, with approximate prevalence of 1:10,000. PCT is frequently associated with hepatitis C virus (HCV), malignant lymphoma and iron overload. Here, we present a case of PCT onset subsequent to hepatitis E virus infection (HEV), characterised by symptoms including skin fragility, haemorrhagic bullous skin exanthema, and onycholysis. The patient was successfully treated by erythrocytapheresis and hydroxychloroquine. After exclusion of other possible causes of PCT, HEV infection was identified as the likely trigger of the disease in this genetically predisposed individual, representing the first reported instance of such an association. Erythrocytapheresis emerged as a viable alternative to phlebotomy for PCT treatment. This case underscores the significance of considering HEV infection in the aetiology of PCT and highlights erythrocytapheresis as a promising therapeutic approach (Ref. 8) .
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30219 - Gastroenterology and hepatology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Bratislavské lekárske listy / Bratislava Medical Journal
ISSN
0006-9248
e-ISSN
1336-0345
Volume of the periodical
125
Issue of the periodical within the volume
10
Country of publishing house
SK - SLOVAKIA
Number of pages
2
Pages from-to
587-588
UT code for WoS article
001334830000001
EID of the result in the Scopus database
2-s2.0-85205335471