4DryField vs. hyalobarrier gel for preventing the recurrence of intrauterine adhesions – a pilot study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F25%3A10482622" target="_blank" >RIV/00064165:_____/25:10482622 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/25:10482622
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=TO9D2L-xMt" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=TO9D2L-xMt</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/13645706.2024.2351829" target="_blank" >10.1080/13645706.2024.2351829</a>
Alternative languages
Result language
angličtina
Original language name
4DryField vs. hyalobarrier gel for preventing the recurrence of intrauterine adhesions – a pilot study
Original language description
Introduction: This was a single-center pilot study that sought to describe an innovative use of 4DryField(R) PH (premix) for preventing the recurrence of intrauterine adhesions (IUAs) after hysteroscopic adhesiolysis in patients with Asherman's syndrome (AS). Material and methods: Twenty-three patients with AS were enrolled and 20 were randomized (1:1 ratio) to intrauterine application of 4DryField(R) PH (n = 10) or Hyalobarrier(R) gel (n = 10) in a single-blind manner. We evaluated IUAs (American Fertility Society [AFS] score) during initial hysteroscopy and second-look hysteroscopy one month later. Patients completed a follow-up symptoms questionnaire three and reproductive outcomes questionnaire six months later. Results: The demographic and clinical characteristics, as well as severity of IUAs, were comparable in both groups. The mean initial AFS score was 9 and 8.5 in the 4DryField(R) PH and Hyalobarrier(R) gel groups, respectively (p = .476). There were no between-group differences in AFS progress (5.9 vs. 5.6, p = .675), need for secondary adhesiolysis (7 vs. 7 patients, p = 1), and the follow-up outcomes. Conclusion: 4DryField(R) PH could be a promising antiadhesive agent for preventing the recurrence of IUAs, showing similar effectiveness and safety to Hyalobarrier(R) gel. Our findings warrant prospective validation in a larger clinical trial.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30214 - Obstetrics and gynaecology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Minimally Invasive Therapy and Allied Technologies
ISSN
1364-5706
e-ISSN
1365-2931
Volume of the periodical
34
Issue of the periodical within the volume
1
Country of publishing house
NO - NORWAY
Number of pages
7
Pages from-to
71-77
UT code for WoS article
001228624900001
EID of the result in the Scopus database
2-s2.0-85193717887