Treatment of Obesity with Thyroid hormones in Europe. Data from the THESIS* Collaboration

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F25%3A10483067" target="_blank" >RIV/00064165:_____/25:10483067 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/25:10483067

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=uTJu--4ezT" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=uTJu--4ezT</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s40618-024-02409-z" target="_blank" >10.1007/s40618-024-02409-z</a>

Result language

angličtina

Original language name

Treatment of Obesity with Thyroid hormones in Europe. Data from the THESIS* Collaboration

Original language description

Purpose: The use of thyroid hormones (TH) to treat obesity is unsupported by evidence as reflected in international guidelines. We explored views about this practice, and associations with respondent characteristics among European thyroid specialists. Methods: Specialists from 28 countries were invited to a survey via professional organisations. The relevant question was whether &quot;Thyroid hormones may be indicated in biochemically euthyroid patients with obesity resistant to lifestyle interventions&quot;. Results: Of 17,232 invitations 5695 responses were received (33% valid response rate; 65% women; 90% endocrinologists). Of these, 290 (5.1%) stated that TH may be indicated as treatment for obesity in euthyroid patients. This view was commoner among non-endocrinologists (8.7% vs. 4.7%, p &lt; 0.01), private practice (6.5% vs. 4.5%, p &lt; 0.01), and varied geographically (Eastern Europe, 7.3%; Southern Europe, 4.8%; Western Europe, 2.7%; and Northern Europe, 2.5%). Respondents from Northern and Western Europe were less likely to use TH than those from Eastern Europe (p &lt; 0.01). Gross national income (GNI) correlated inversely with this view (OR 0.97, CI: 0.96-0.97; p &lt; 0.001). Having national guidelines on hypothyroidism correlated negatively with treating obesity with TH (OR 0.71, CI: 0.55-0.91). Conclusions: Despite the lack of evidence, and contrary to guidelines&apos; recommendations, about 5% of respondents stated that TH may be indicated as a treatment for obesity in euthyroid patients resistant to life-style interventions. This opinion was associated with (i) respondent characteristics: being non-endocrinologist, working in private practice, treating a small number of hypothyroid patients annually and (ii) national characteristics: prevalence of obesity, Eastern Europe, low GNI and lack of national hypothyroidism guidelines.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30202 - Endocrinology and metabolism (including diabetes, hormones)

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Endocrinological Investigation

ISSN

0391-4097

e-ISSN

1720-8386

Volume of the periodical

48

Issue of the periodical within the volume

1

Country of publishing house

IT - ITALY

Number of pages

12

Pages from-to

201-212

UT code for WoS article

001248305800001

EID of the result in the Scopus database

2-s2.0-85196034108