Case Report: Hybrid closed-loop insulin pump can significantly improve awareness of hypoglycemia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F25%3A10497699" target="_blank" >RIV/00064165:_____/25:10497699 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/25:10497699
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=K~sRz91t9i" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=K~sRz91t9i</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/fcdhc.2025.1536038" target="_blank" >10.3389/fcdhc.2025.1536038</a>
Alternative languages
Result language
angličtina
Original language name
Case Report: Hybrid closed-loop insulin pump can significantly improve awareness of hypoglycemia
Original language description
Impaired awareness of hypoglycemia remains an issue even in the era of modern technologies, as patients with type 1 diabetes (T1DM) face stricter requirements for glycemic targets. The evaluation of hypoglycemia awareness can be accomplished using questionnaires (Clarke and Gold scores) in combination with clinical appearance and sensor data. A 45-year-old man with T1DM was referred to our clinic in July 2019 due to impaired hypoglycemia awareness and repeated severe hypoglycemic episodes resulting in unconsciousness. At that time, he was driving both a car and a motorcycle. Despite good compliance, increased target values and implementation of continuous glucose monitoring (CGM) with alarms, prolonged hypoglycemias were not eliminated. Therefore, the patient was referred for pancreatic islet transplantation, but he decided not to undergo. In May 2021, his driving license was suspended, which eventually led him to accept treatment with a hybrid closed-loop insulin pump (AID). Shortly after initiation, he achieved satisfactory glycemic control, reduced time spent in hypoglycemia, and had no severe hypoglycemic episodes. According to the questionnaires, the hypoglycemia awareness has improved and his driving license was reinstated. This case study highlights the critical importance of identifying impaired awareness of hypoglycemia, its potential social impacts, and the opportunities for using new technologies to reverse this complication.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30202 - Endocrinology and metabolism (including diabetes, hormones)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Frontiers in Clinical Diabetes and Healthcare
ISSN
2673-6616
e-ISSN
2673-6616
Volume of the periodical
6
Issue of the periodical within the volume
February
Country of publishing house
CH - SWITZERLAND
Number of pages
5
Pages from-to
1536038
UT code for WoS article
001438648700001
EID of the result in the Scopus database
2-s2.0-86000656760