Reasons for death in patients receiving ECPR for refractory out-of-hospital cardiac arrest

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F25%3A10500024" target="_blank" >RIV/00064165:_____/25:10500024 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/25:10500024

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=TD_Vm_B8cW" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=TD_Vm_B8cW</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.resuscitation.2025.110615" target="_blank" >10.1016/j.resuscitation.2025.110615</a>

Result language

angličtina

Original language name

Reasons for death in patients receiving ECPR for refractory out-of-hospital cardiac arrest

Original language description

Background: There are limited data on the causes of death in patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR). This study aimed to analyse the causes of death among patients who received ECPR following out-of-hospital cardiac arrest (OHCA). Methods: In this post-hoc analysis of a prospective registry, the causes of death were categorized using a predefined method specifically developed for cardiac arrest patients. Two investigators independently assigned each patient to one of five predefined categories of death, with interrater reliability measured using Fleiss&apos; kappa. Results: From January 2012 to December 2023, a total of 1,219 OHCA patients were admitted to the hospital, of whom 210 underwent ECPR. Among these, 152 (72.3%) patients died during their index hospitalization. The median age of deceased patients was 57 years, with 80.9% being male, and the median time to ECPR initiation was 62 min (IQR: 53-72). Interrater agreement was 0.81. The most common primary cause of death was refractory shock (75/152 patients, 49.3%), followed by neurological injury (69/152 patients, 45.3%), rearrest (7/152 patients, 4.6%), and comorbidities (1/152 patients, 0.6%). Conclusions: Refractory shock was the leading cause of death among our cohort of ECPR patients, followed closely by neurological complications, while other causes were rare.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30221 - Critical care medicine and Emergency medicine

Project

<a href="/en/project/NW25-06-00458" target="_blank" >NW25-06-00458: INNOVATIVE ASSESSMENTS FOR EARLY NEUROPROGNOSTICATION OF PATIENTS WITH REFRACTORY CARDIAC ARREST TREATED BY ECPR (EXTRACORPOREAL CARDIOPULMONARY RESUSCITATION)</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Resuscitation

ISSN

0300-9572

e-ISSN

1873-1570

Volume of the periodical

213

Issue of the periodical within the volume

August

Country of publishing house

IE - IRELAND

Number of pages

5

Pages from-to

110615

UT code for WoS article

001520775600001

EID of the result in the Scopus database

2-s2.0-105003808261