Evidence of an excellent international cooperation in the management of chronic thromboembolic pulmonary hypertension
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F25%3A10501939" target="_blank" >RIV/00064165:_____/25:10501939 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/25:10501939
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=rfTOvEBeD4" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=rfTOvEBeD4</a>
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
Evidence of an excellent international cooperation in the management of chronic thromboembolic pulmonary hypertension
Original language description
Background: Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare disease requiring centralized management in specialized centres. Balloon pulmonary angioplasty (BPA) is a treatment option for patients ineligible for pulmonary endarterectomy (PEA) or with residual pulmonary hypertension after PEA. Smaller countries collaborate with larger expert centres to ensure comprehensive care. Methods: This retrospective study assessed international collaboration in CTEPH interventional treatment based on data from 43 BPA procedures performed on 13 patients. Results: Significant improvements were observed between baseline and post-BPA parameters. WHO functional class improved from 23% to 77% in class I/II (p = 0.019), and the 6-minute walk distance increased by 191 meters (p = 0.009). Mean pulmonary artery pressure decreased by 27.9% (p < 0.001), and pulmonary vascular resistance was reduced by 35.3% (p = 0.025). Echocardiographic follow-ups demonstrated enhanced right ventricular function, alongside a reduction in the tricuspid regurgitation gradient by an average of 31 mmHg (40.2%; p < 0.001). A total of 4 non-fatal complications (9.3% of procedures) were observed, with no fatal complications reported. Conclusion: This study confirmed significant clinical and hemodynamic improvements following BPA, with outcomes comparable to those achieved in large expert centres. The rate of procedure-related complications was acceptable, highlighting the potential for successful international collaboration in CTEPH management (Tab. 2, Fig. 2, Ref. 18).
Czech name
—
Czech description
—
Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
—
OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
—
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Lekarsky Obzor
ISSN
0457-4214
e-ISSN
—
Volume of the periodical
74
Issue of the periodical within the volume
4
Country of publishing house
SK - SLOVAKIA
Number of pages
8
Pages from-to
124-131
UT code for WoS article
—
EID of the result in the Scopus database
2-s2.0-105000419277