Untreated incomplete ALCAPA in an adult resulting in mitral regurgitation and reduced left ventricular ejection fraction: case report
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F25%3A10504255" target="_blank" >RIV/00064165:_____/25:10504255 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/25:10504255
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=8zV30NKpG7" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=8zV30NKpG7</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/ehjcr/ytaf482" target="_blank" >10.1093/ehjcr/ytaf482</a>
Alternative languages
Result language
angličtina
Original language name
Untreated incomplete ALCAPA in an adult resulting in mitral regurgitation and reduced left ventricular ejection fraction: case report
Original language description
BACKGROUND: Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital malformation, with an incidence ranging from 1 in 300 000 to 1 in 30 000 live births. Incomplete ALCAPA is defined as an abnormal origin of either the left anterior descending coronary artery (LAD) or the circumflex artery from the aorta. It may also present as ALCAPA with duplication of one of these arteries due to an additional branch arising from the aorta. CASE SUMMARY: The case report presents a man diagnosed with dilated cardiomyopathy at the age of 29. Despite repeated echocardiographic examinations, the diagnosis of incomplete ALCAPA (additional LAD arising from the aorta) as the aetiology of the dilated cardiomyopathy with reduced left ventricular ejection fraction and severe mitral regurgitation was only established at age 57. The patient underwent surgical correction of the ALCAPA and mitral valve repair. Despite optimal surgical intervention, only minimal postoperative improvement in the left ventricular ejection fraction was observed. DISCUSSION: According to guidelines, computed tomography angiography is the most effective diagnostic method for anomalous origin of coronary artery from the pulmonary artery (ACAPA). Due to ACAPA's extreme rarity, standard indications for surgical intervention in incomplete ALCAPA are not established. Surgical correction appears most suitable for symptomatic patients. It should also be considered for asymptomatic patients with ventricular dysfunction or myocardial ischaemia caused by the coronary anomaly.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Heart Journal - Case Reports
ISSN
2514-2119
e-ISSN
2514-2119
Volume of the periodical
9
Issue of the periodical within the volume
10
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
ytaf482
UT code for WoS article
001593826600001
EID of the result in the Scopus database
2-s2.0-105019371378