Prolonged repolarization in atrial septal defect: An example of mechanoelectrical feedback due to right ventricular volume overload
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F16%3AN0000206" target="_blank" >RIV/00064173:_____/16:N0000206 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/16:10324091 RIV/00216208:11120/16:43911611 RIV/00064203:_____/16:10324091
Result on the web
<a href="http://dx.doi.org/10.1016/j.hrthm.2016.01.032" target="_blank" >http://dx.doi.org/10.1016/j.hrthm.2016.01.032</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.hrthm.2016.01.032" target="_blank" >10.1016/j.hrthm.2016.01.032</a>
Alternative languages
Result language
angličtina
Original language name
Prolonged repolarization in atrial septal defect: An example of mechanoelectrical feedback due to right ventricular volume overload
Original language description
BACKGROUND: Prolonged corrected QT (QTc) intervals are frequently observed in children before atrial septal defect (ASD) closure in our department. OBJECTIVE: The aim of the study was to assess the effect of long-term right ventricular volume overload on repolarization. METHODS: QRS, QT, and JT intervals were measured manually in leads II and V5 of a standard 12-lead electrocardiogram in 45 children with an isolated ASD a day before and at least 6 months after ASD closure. QT intervals were corrected for heart rate using the Bazett, Fridericia, Framingham, and Hodges formulas. Each QTc interval calculated using the Bazett formula was compared to sex- and age-matched normal values. RESULTS: Individual QTc intervals shortened significantly (P < .001) using all correction formulas, whereas the QRS duration did not change. The prevalence of prolonged QTc interval decreased from 22.2% to 2.2% after shunt closure (P = .007). CONCLUSION: The QTc interval shortens significantly after the closure of a hemodynamically relevant ASD in childhood. This phenomenon is independent of the used QT correction formula and may reflect a mechanoelectrical feedback associated with right ventricular volume overload.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Heart Rhythm
ISSN
1547-5271
e-ISSN
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Volume of the periodical
13
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
6
Pages from-to
1303-1308
UT code for WoS article
000376334800018
EID of the result in the Scopus database
2-s2.0-84960153286