Commentary on management of osteoporosis in advanced CKD - common view of a nephrologist and a bone specialist

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F19%3AN0000175" target="_blank" >RIV/00064173:_____/19:N0000175 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.4158/EP-2018-0311" target="_blank" >https://doi.org/10.4158/EP-2018-0311</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Commentary on management of osteoporosis in advanced CKD - common view of a nephrologist and a bone specialist

Original language description

The manuscript summarizes current consensual view of bone specialists and a nephrologist of the management of osteoporosis in patients with advanced chronic kidney disease (CKD) as a part of CKD-MBD (mineral and bone disorder associated with CKD). Osteoporosis has been recently accepted as a subunit of CKD-MBD, occurring in up to one third of advanced CKD patients, with fractures being the most severe complication. Diagnosis and differential diagnosis is currently based on non-invasive procedures (densitometry, laboratory assessment of calcium-phosphate metabolism and bone turnover); originally recommended bone biopsy is reserved for unclear cases. Specific treatment is complicated since majority of anti-osteoporotic drugs are contraindicated in advanced CKD and all of them lack robust data on effectiveness and safety in this specific population.

Czech name

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Czech description

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Type

O - Miscellaneous

CEP classification

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OECD FORD branch

30202 - Endocrinology and metabolism (including diabetes, hormones)

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů