Adalimumab Biosimilar-Induced Severe Paradoxical Palmoplantar Pustulosis in a Patient with Psoriasis and Psoriatic Arthritis Successfully Treated with Ixekizumab

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F22%3A43922689" target="_blank" >RIV/00064173:_____/22:43922689 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11120/22:43922689

Result on the web

<a href="https://doi.org/10.1007/s13555-021-00672-z" target="_blank" >https://doi.org/10.1007/s13555-021-00672-z</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s13555-021-00672-z" target="_blank" >10.1007/s13555-021-00672-z</a>

Result language

angličtina

Original language name

Adalimumab Biosimilar-Induced Severe Paradoxical Palmoplantar Pustulosis in a Patient with Psoriasis and Psoriatic Arthritis Successfully Treated with Ixekizumab

Original language description

Psoriasis vulgaris is a chronic immune-mediated inflammatory disease of the skin. Biologic therapy has been available for more than ten years and has become one of the standard treatments for patients with moderate to severe psoriasis. Firstly, drugs against tumour necrosis factor alpha (TNF-α) were used and only later drugs against different interleukins (IL) like 17 or 23 became available. Side effects of biologic therapy include paradoxical adverse events (PAE) like palmoplantar pustular reaction, especially with anti-TNF-α drugs. We present a case of a 49-year old female diabetic patient with psoriasis and psoriatic arthritis treated with an adalimumab biosimilar who developed a severe PAE of the palmoplantar pustular type. Adalimumab was stopped and the patient was switched to ixekizumab which was successful. When a paradoxical reaction develops during biologic therapy, especially when it is severe like in our patient, switching to another class of biologics is advised.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30216 - Dermatology and venereal diseases

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Dermatology and Therapy

ISSN

2193-8210

e-ISSN

2190-9172

Volume of the periodical

12

Issue of the periodical within the volume

2

Country of publishing house

DE - GERMANY

Number of pages

5

Pages from-to

605-609

UT code for WoS article

000745815600001

EID of the result in the Scopus database

2-s2.0-85123471275