Clinical and radiological factors predicting stroke outcome after successful mechanical intervention in anterior circulation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F22%3A43923296" target="_blank" >RIV/00064173:_____/22:43923296 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/22:43923296
Result on the web
<a href="https://doi.org/10.1093/eurheartjsupp/suac010" target="_blank" >https://doi.org/10.1093/eurheartjsupp/suac010</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/eurheartjsupp/suac010" target="_blank" >10.1093/eurheartjsupp/suac010</a>
Alternative languages
Result language
angličtina
Original language name
Clinical and radiological factors predicting stroke outcome after successful mechanical intervention in anterior circulation
Original language description
The recanalization effect of large-vessel occlusion (LVO) in anterior circulation is well documented but only some patients benefit from endovascular treatment. We analysed clinical and radiological factors determining clinical outcome after successful mechanical intervention. We included 146 patients from the Prague 16 study enrolled from September 2012 to December 2020, who had initial CT/CTA examination and achieved good recanalization status after mechanical intervention (TICI 2b-3). One hundred and six (73%) patients achieved a good clinical outcome (modified Rankin Scale 0-2 in 3 months). It was associated with age, leptomeningeal collaterals (LC), onset to intervention time, ASPECTS, initial NIHSS, and leukoaraiosis (LA) in univariate analysis. The regression model identified good collateral status [odds ratio (OR) 5.00, 95% confidence interval (CI) 1.91-13.08], late thrombectomy (OR 0.24, 95% CI 0.09-0.65), LA (OR 0.44, 95% CI 0.19-1.00), ASPECTS (OR 1.45, 95% CI 1.08-1.95), and NIHSS score (OR 0.86, 95% CI 0.78-0.95) as independent outcome determinants. In the late thrombectomy subgroup, 14 out of 33 patients (42%) achieved a favourable clinical outcome, none of whom with poor collateral status. The presence of LC and absence of LA predicts a good outcome in acute stroke patients after successful recanalization of LVO in anterior circulation. Late thrombectomy was associated with higher rate of unfavourable clinical outcome. Nevertheless, collateral status in this subgroup was validated as a reliable selection criterion.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
<a href="/en/project/EF16_026%2F0008388" target="_blank" >EF16_026/0008388: Interventional treatment of life-threatening cardiovascular diseases</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Heart Journal: Supplements
ISSN
1520-765X
e-ISSN
1554-2815
Volume of the periodical
24
Issue of the periodical within the volume
Suppl. B
Country of publishing house
GB - UNITED KINGDOM
Number of pages
5
Pages from-to
"B48"-"B52"
UT code for WoS article
000780488200010
EID of the result in the Scopus database
2-s2.0-85132415289