Acute myeloid leukemia with variant t(8;10;21)

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F22%3A43923985" target="_blank" >RIV/00064173:_____/22:43923985 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/22:43923985
Result on the web
<a href="https://doi.org/10.1016/j.lrr.2022.100350" target="_blank" >https://doi.org/10.1016/j.lrr.2022.100350</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.lrr.2022.100350" target="_blank" >10.1016/j.lrr.2022.100350</a>

Result language
angličtina
Original language name
Acute myeloid leukemia with variant t(8;10;21)
Original language description
The t(8;21)(q22;q22) is one of the most common chromosomal abnormalities in acute myeloid leukemia (AML). Approximately 3-4% of AML cases are associated with additional chromosomal abnormalities. Their impact on the prognosis of the disease remains to be established. Here we report a case of t(8;10;21) AML with mutated c-KIT that shared key morphological features with classical t(8;21) leukemias, including the M2 morphology pattern and CD34, HLA-DR phenotype. The 63-year-old female was treated with two inductioncontaining Daunoribicine and Cytarabine and four cycles of intermediate-dose Cytarabine (1.5 g/m(2)) and achieved long-lasting remission.
Czech name
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Czech description
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Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30205 - Hematology

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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