Janus Kinase Inhibitors in the Treatment of Alopecia Areata
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F23%3A43925129" target="_blank" >RIV/00064173:_____/23:43925129 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/23:43925129
Result on the web
<a href="https://doi.org/10.14712/23362936.2023.1" target="_blank" >https://doi.org/10.14712/23362936.2023.1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.14712/23362936.2023.1" target="_blank" >10.14712/23362936.2023.1</a>
Alternative languages
Result language
angličtina
Original language name
Janus Kinase Inhibitors in the Treatment of Alopecia Areata
Original language description
Alopecia areata is a disease of autoimmune origin which causes non scarring hair loss. The extent of alopecia varies from a small patch to complete scalp and body hair loss, which can have huge psychosocial impact for those affected. Treatment modalities which have been used so far included nonspecific immunosuppressive medications, such as corticosteroids, cyclosporine, and methotrexate, or topical immunomodulators, such as diphencyprone, dithranol, and squaric acid dibutylester. The recognition of the importance of Janus kinase pathway in alopecia areata pathogenesis enabled more specific approaches in treatment. Positive outcomes of Janus kinase inhibitors in several trials granted approval for baricitinib which became the first on-label treatment for alopecia areata. The aim of this review is to summarize the role, efficacy and safety of several Janus kinase inhibitors in alopecia areata.
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30216 - Dermatology and venereal diseases
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Prague Medical Report
ISSN
1214-6994
e-ISSN
2336-2936
Volume of the periodical
124
Issue of the periodical within the volume
1
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
11
Pages from-to
5-15
UT code for WoS article
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EID of the result in the Scopus database
2-s2.0-85147894003