Surface Modification of Artificial Implants by Hybrid Nanolayers: Antimicrobial Surface Finishing and Strength Tests

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F23%3A43926312" target="_blank" >RIV/00064173:_____/23:43926312 - isvavai.cz</a>

Alternative codes found

RIV/46747885:24220/23:00011925 RIV/46747885:24510/23:00011925 RIV/00216208:11120/23:43926312

Result on the web

<a href="https://doi.org/10.1159/000534333" target="_blank" >https://doi.org/10.1159/000534333</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1159/000534333" target="_blank" >10.1159/000534333</a>

Result language

angličtina

Original language name

Surface Modification of Artificial Implants by Hybrid Nanolayers: Antimicrobial Surface Finishing and Strength Tests

Original language description

INTRODUCTION: The aim of this work was the evaluation of surface modification in surgery of normally used hernia implants and thus improving their antimicrobial properties. The modification consisted of applying hybrid nanolayers with immobilized antiseptic substances (metal cations of Ag, Cu, and Zn) by sol-gel method which ensures prolonged effect of these substances and thus enables a greater resistance of the implant towards infection. In this work, attention is drawn to the issue of applying hybrid nanolayers, activation of mesh surfaces by physical plasma modification or ultraviolet C (UV C) radiation, and influence of these modifications on the mechanical properties of the final meshes. Next work will continue concentrating on the issue of antimicrobial efficacy and eventual toxicity of the prepared layers. MATERIALS AND METHODS: Present-day materials of the most commonly used types of implants for reconstruction of the abdominal wall in surgery (polypropylene, polyester, polyvinylidenefluoride) were tested. Optimum conditions of application of nanolayers by sol-gel method and their thermal stabilization were examined first. Surface modification was verified by scanning electron microscope. The surface of implants was first activated for better adhesion by plasma treatment or UV radiation after preliminary tests. Maximum strength and ductility after activation and hybrid nanolayer modification were objectively measured on a universal Testometric tensile testing machine. RESULTS: The results of surface activation of the meshes (by both plasma treatment or UV C radiation) provided similar and satisfactory results, and particular conditions differed based on the type of material of the mesh. Usage of antimicrobial sol AD30 diluted by isopropyl alcohol in 1:1 proportion appear to be optimal. All tested cases of meshes activated by plasma treatment or UV C radiation and with applied nanolayer concluded in a slight reduction of mechanical properties in modified meshes in comparison with the original ones. However, a slight reduction of test values was not of clinical importance. CONCLUSION: It was verified that surface modification of implants by sol-gel method is effective and technically possible, providing hopeful results.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30212 - Surgery

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Surgical Research

ISSN

0014-312X

e-ISSN

1421-9921

Volume of the periodical

64

Issue of the periodical within the volume

4

Country of publishing house

CH - SWITZERLAND

Number of pages

14

Pages from-to

376-389

UT code for WoS article

001128172000006

EID of the result in the Scopus database

2-s2.0-85178562301