The headshake enhances oculomotor response to galvanic vestibular stimulation in healthy subjects
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F24%3A43926724" target="_blank" >RIV/00064173:_____/24:43926724 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/24:10479871 RIV/00179906:_____/24:10479871
Result on the web
<a href="https://doi.org/10.1016/j.clinph.2024.02.018" target="_blank" >https://doi.org/10.1016/j.clinph.2024.02.018</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.clinph.2024.02.018" target="_blank" >10.1016/j.clinph.2024.02.018</a>
Alternative languages
Result language
angličtina
Original language name
The headshake enhances oculomotor response to galvanic vestibular stimulation in healthy subjects
Original language description
OBJECTIVE: To investigate whether a headshake applied during galvanic vestibular stimulation (GVS) can enhance GVS-induced nystagmus in healthy subjects. METHODS: In nineteen healthy participants, we evaluated an average slow-phase velocity (aSPV) of nystagmus in a head-still and after the headshake conditions, with/out the bitemporal 2 mA GVS. The GVS was applied also with polarity congruent (supporting) or incongruent (suppressing) to any preexisting spontaneous nystagmus. RESULTS: The orientation of GVS-induced nystagmus depended on GVS polarity. In the head-still condition, the GVS-induced nystagmus in 14 subjects (74%) for congruent and in 12 subjects (63%) for incongruent GVS. During headshake, we recorded nystagmus in 16 subjects (84%) for congruent and 15 subjects (79%) for incongruent GVS. The aSPV of congruent GVS-induced nystagmus was higher (p = 0.0003) by 1.33 (SE 0.26) deg/s for headshake compared to head-still condition. The aSPV of incongruent GVS also induced higher nystagmus (p = 0.0014) by 1.24 (SE 0.28) deg/s for the headshake condition. CONCLUSION: Our study adds a new principle to the knowledge of the central processing of a GVS response in healthy subjects. The GVS-safety profile of current up to 2 mA was sufficient to elicit a significant GVS nystagmus response in a head-still position in 63% and after a headshake in 79%. Compared to the GVS head-still condition, a headshake enhanced the GVS-induced nystagmus more than twice. SIGNIFICANCE: The headshake helps to identify GVS-induced nystagmus, which can be weak or absent during the head-still condition.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30206 - Otorhinolaryngology
Result continuities
Project
<a href="/en/project/EF19_073%2F0016935" target="_blank" >EF19_073/0016935: Grant schemes at Charles University</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Clinical Neurophysiology
ISSN
1388-2457
e-ISSN
1872-8952
Volume of the periodical
161
Issue of the periodical within the volume
May
Country of publishing house
IE - IRELAND
Number of pages
7
Pages from-to
10-16
UT code for WoS article
001205759900001
EID of the result in the Scopus database
2-s2.0-85186611664