Chemical, Physical, and Biological Corneal Decellularization Methods: A Review of Literature

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F24%3A43926913" target="_blank" >RIV/00064173:_____/24:43926913 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/24:43926913
Result on the web
<a href="https://doi.org/10.1155/2024/1191462" target="_blank" >https://doi.org/10.1155/2024/1191462</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2024/1191462" target="_blank" >10.1155/2024/1191462</a>

Result language
angličtina
Original language name
Chemical, Physical, and Biological Corneal Decellularization Methods: A Review of Literature
Original language description
The cornea is one of the most commonly transplanted tissues worldwide. It is used to restore vision when severe visual impairment or blindness occurs in patients with corneal diseases or after trauma. Due to the global shortage of healthy donor corneas, decellularized corneal tissue has significant potential as an alternative to corneal transplantation. It preserves the native and biological ultrastructure of the cornea and, therefore, represents the most promising scaffold. This article discusses different methods of corneal decellularization based on the current literature. We searched PubMed.gov for articles from January 2009 to December 2023 using the following keywords: corneal decellularization, decellularization methods, and corneal transplantation. Although several methods of decellularization of corneal tissue have been reported, a universal standardised protocol of corneal decellularization has not yet been introduced. In general, a combination of decellularization methods has been used for efficient decellularization while preserving the optimal properties of the corneal tissue.
Czech name
—
Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30207 - Ophthalmology

Project
<a href="/en/project/TO01000099" target="_blank" >TO01000099: The establishment of advanced cell therapy for the treatment of limbal stem cell deficiency in the Czech Republic.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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