Resilience in Rectal Cancer Treatment: Lessons from the COVID-19 Era in Czech Republic

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F24%3A43927262" target="_blank" >RIV/00064173:_____/24:43927262 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11120/24:43927262 RIV/65269705:_____/24:00080216

Result on the web

<a href="https://doi.org/10.2147/TCRM.S455332" target="_blank" >https://doi.org/10.2147/TCRM.S455332</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2147/TCRM.S455332" target="_blank" >10.2147/TCRM.S455332</a>

Result language

angličtina

Original language name

Resilience in Rectal Cancer Treatment: Lessons from the COVID-19 Era in Czech Republic

Original language description

INTRODUCTION: The management of patients with COVID-19 infection has placed great pressure on the healthcare systems around the world. The aim of this study was to investigate the impact of the COVID-19 pandemic on the treatment outcomes of patients with rectal cancer by comparing them to those of patients with the same diagnosis in the pre-pandemic period. METHODS: Retrospective data analysis of patients undergoing multimodal treatment for rectal cancer at the four university hospitals during the COVID-19 pandemic (2020-2021) and the 2-year pre-pandemic period (2018-2019). RESULTS: A total of 693 patients (319 in the pre-pandemic period and 374 in the pandemic period) with rectal cancer were included in the study. The demographic and clinical characteristics of patients in both study periods were comparable, as was the spectrum of surgical procedures. Palliative surgery was more common in the pandemic period (18% vs 13%, p=0.084). The proportion of patients undergoing minimally invasive surgery was higher during the COVID-19 pandemic (p=0.025). There were no statistically significant differences between the study periods in the incidence/severity of post-operative complications, 30-day mortality and length of hospital stay. The number of positive resection margins was similar (5% vs 5%). Based on these results, COVID-19 had no effect on the postoperative morbidity and mortality in patients undergoing surgery for rectal cancer. Neoadjuvant treatment was more common in the pre-pandemic period (50% vs 45%). Long-course RT was predominantly offered in the pre-pandemic period, short-course RT during the pandemic. Significantly shorter &quot;diagnosis-surgery&quot; intervals were observed during the pandemic (23 days vs 33 days, p=0.0002). The &quot;surgery-adjuvant therapy&quot; interval was similar in both analysed study periods (p=0.219). CONCLUSION: Our study showed, that despite concerns about the COVID-19 pandemic, multimodal treatment of rectal cancer was associated with unchanged postoperative morbidity rates, increased frequency of short-course neoadjuvant RT administration and shorter &quot;diagnosis-surgery&quot; intervals.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30204 - Oncology

Project

<a href="/en/project/NU22-C-113" target="_blank" >NU22-C-113: Effect of COVID-19 pandemic on surgical care for patients with solid tumors of gastrointestinal tract in the Czech Republic:</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Therapeutics and Clinical Risk Management

ISSN

1178-203X

e-ISSN

1178-203X

Volume of the periodical

20

Issue of the periodical within the volume

June

Country of publishing house

NZ - NEW ZEALAND

Number of pages

7

Pages from-to

373-379

UT code for WoS article

001248758200001

EID of the result in the Scopus database

2-s2.0-85197107212