Predictors of spontaneous intracerebral hemorrhage mortality: a community-based study in Brno, Czech Republic

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F24%3A43927430" target="_blank" >RIV/00064173:_____/24:43927430 - isvavai.cz</a>

Alternative codes found

RIV/00159816:_____/24:00080310 RIV/00216224:14110/24:00136768 RIV/00216208:11120/24:43927430 RIV/65269705:_____/24:00080310

Result on the web

<a href="https://doi.org/10.1007/s13760-024-02612-y" target="_blank" >https://doi.org/10.1007/s13760-024-02612-y</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s13760-024-02612-y" target="_blank" >10.1007/s13760-024-02612-y</a>

Result language

angličtina

Original language name

Predictors of spontaneous intracerebral hemorrhage mortality: a community-based study in Brno, Czech Republic

Original language description

BACKGROUND AND OBJECTIVE: Intracerebral hemorrhage (ICH) is a serious medical condition with high mortality. However, factors leading to long-term mortality after ICH are largely unclear. The aim of this community-based study is to assess predictors of long-term mortality after spontaneous ICH. METHODS: We identified all patients admitted with spontaneous ICH to hospitals with a certified stroke unit in Brno, the second largest city in the Czech Republic (CR), in 2011, the year of the Czech Population and Housing Census. We reviewed their medical records for risk factors, radiographic parameters, and measures of post-stroke neurological deficit [National Institutes of Health Stroke Scale (NIHSS)]. Using the dates of death from the Czech National Mortality Register, we calculated mortality at 30 days, six months, one year, and three years after the ICH. Multivariate analysis with forward stepwise logistic regression was performed to determine independent predictors of mortality (p &lt; 0.05). RESULTS: In 2011, 1086 patients with stroke were admitted to the four stroke-certified hospitals in Brno, CR. Of these, 134 had spontaneous ICH, with complete data available in 93 of them entering the final analysis. The mortality at 30 days, 6 months, 1 year, and 3 years post-ICH was 34%, 47%, 51%, and 63%, respectively. The mortality was highest in the first few days post-event, with 50% of patients dying in 255 days and average survival being 884 +- 90 days. Both NIHSS and modified ICH (MICH) score showed to be strong and reliable predictors of short- as well as long-term mortality; the risk of death post-ICH increased with older age and size of ICH. Other risk factors contributing to higher, primarily shorter-term mortality included history of cardiac failure, myocardial infarction, or atrial fibrillation. CONCLUSIONS: In our community-based study, we found that severity of neurological deficit at admission (NIHSS), combined with age and size of ICH, well predicted short- as well as long-term mortality after spontaneous ICH. A history of cardiac failure, myocardial infarction, or atrial fibrillation at presentation were also predictors of mortality, underscoring the need for optimal cardiac management in patients with ICH.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30210 - Clinical neurology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta Neurologica Belgica

ISSN

0300-9009

e-ISSN

2240-2993

Volume of the periodical

124

Issue of the periodical within the volume

6

Country of publishing house

DE - GERMANY

Number of pages

14

Pages from-to

1945-1958

UT code for WoS article

001284655800001

EID of the result in the Scopus database

2-s2.0-85200347049