Survival after surgery for acute type A aortic dissection in octogenarians
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F24%3A43927828" target="_blank" >RIV/00064173:_____/24:43927828 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/24:43927828
Result on the web
<a href="https://doi.org/10.26599/1671-5411.2024.11.009" target="_blank" >https://doi.org/10.26599/1671-5411.2024.11.009</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.26599/1671-5411.2024.11.009" target="_blank" >10.26599/1671-5411.2024.11.009</a>
Alternative languages
Result language
angličtina
Original language name
Survival after surgery for acute type A aortic dissection in octogenarians
Original language description
OBJECTIVE: To evaluate the benefits of surgical repair acute type A aortic dissection (ATAAD) on survival of octogenarians. METHODS: Patients who underwent surgery for acute ATAAD from the multicenter European Registry of Type A Aortic Dissection (ERTAAD) were the subjects of the present analysis. RESULTS: 326 (8.4%) patients were aged >= 80 years. Among 280 propensity score matched pairs, in-hospital mortality was 30.0% in patients aged >= 80 years and 20.0% in younger patients (P = 0.006), while 10-year mortality were 93.2% and 48.0%, respectively (P < 0.001). The hazard of mortality was higher among octogenarians up to two years after surgery, but it became comparable to that of younger patients up to 5 years. Among patients who survived 3 months after surgery, 10-year relative survival was 0.77 in patients aged < 80 years, and 0.46 in patients aged >= 80 years. Relative survival of octogenarians decreased markedly 5 years after surgery. Age >= 85 years, glomerular filtration rate, preoperative invasive ventilation, preoperative mesenteric mal-perfusion and aortic root replacement were independent predictors of in-hospital mortality among octogenarians (AUC = 0.792; E:O ratio = 0.991; CITL = 0.016; slope = 1.096). An additive score was developed. A risk score <= 1 was observed in 68.4% of patients, and their in-hospital mortality was 20.9%. CONCLUSIONS: Provided a thoughtful patient selection, surgery may provide a survival benefit in patients aged >= 80 years with ATAAD that, when compared to younger patients and the general population, may last up to 5 years after the procedure. These findings have significant epidemiologic and clinical relevance because of the increasing longevity of the population of the Western countries.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
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Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Geriatric Cardiology
ISSN
1671-5411
e-ISSN
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Volume of the periodical
21
Issue of the periodical within the volume
11
Country of publishing house
CN - CHINA
Number of pages
11
Pages from-to
1015-1025
UT code for WoS article
001384887100002
EID of the result in the Scopus database
2-s2.0-85211992002