Clinical Pharmaceutical Care in Nursing Home Residents as a Cornerstone for Drug-Related Problems Identification

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F25%3A43928441" target="_blank" >RIV/00064173:_____/25:43928441 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/25:10498132 RIV/00216208:11120/25:43928441 RIV/00216208:11130/25:10498132 RIV/27283933:_____/25:N0000034 and 2 more

Result on the web

<a href="https://doi.org/10.1111/cts.70222" target="_blank" >https://doi.org/10.1111/cts.70222</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/cts.70222" target="_blank" >10.1111/cts.70222</a>

Result language

angličtina

Original language name

Clinical Pharmaceutical Care in Nursing Home Residents as a Cornerstone for Drug-Related Problems Identification

Original language description

Rational prescribing in geriatrics represents an important ethical as well as socio-economic issue. The aim of this project was to analyze the drug-related problems (DRPs) among the Czech nursing home residents and increase public awareness of further possible employment of clinical pharmacists in social care. The project was designed as a multicenter observational study. A total of 16 nursing homes and 800 participants with an average age of 84.6 +- 7.3 years were included in the study. Of them, a DRP was noted in 93.3% of people. The total amount of DRPs identified was 2215, which means an average of 2.8 +- 1.6 DRPs per patient. The most common DRPs identified were &apos;overtreatment&apos; (19.5%), &apos;undertreatment&apos; (12.8%), inappropriate dose (10.6%), recommendations for laboratory monitoring (10.4%) and adverse effects (10.3%). Of different drug classes, BZDs (OR 16.6, 95% CI 1.0-270.2), PPIs (OR 2.5, 95% CI 1.1-5.6) and NSAIDs (OR 4.4, 95% CI 1.1-18.3) were identified to be most commonly associated with DRPs. The risk of DRP identification clearly increased with the number of drugs used, with seven drugs demonstrated as the best cut-off for predicting DRP identification (AUC 0.842, sensitivity 0.602; specificity 0.796). &apos;SENIOR&apos; project has confirmed a high rate of excessive polypharmacy among nursing home residents in the Czech republic resulting in high risk of potential and manifested DRPs. The project emphasized the role of clinical pharmacists in optimizing safety and effectiveness of treatment among older nursing home residents.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30104 - Pharmacology and pharmacy

Project

<a href="/en/project/EH22_008%2F0004607" target="_blank" >EH22_008/0004607: New Technologies for Translational Research in Pharmaceutical Sciences /NETPHARM</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Clinical and Translational Science

ISSN

1752-8054

e-ISSN

1752-8062

Volume of the periodical

18

Issue of the periodical within the volume

5

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

"e70222"

UT code for WoS article

001490943700001

EID of the result in the Scopus database

2-s2.0-105005578064