Current standards in the treatment of metastatic breast cancer with focus on Lapatinib: a review by a Central European Consensus Panel

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F10%3A%230000091" target="_blank" >RIV/00064190:_____/10:#0000091 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/10:00051832 RIV/00209805:_____/10:#0000274

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Current standards in the treatment of metastatic breast cancer with focus on Lapatinib: a review by a Central European Consensus Panel

Original language description

In breast cancer, early detection as well as new developments in therapeutic options has resulted in less patients presenting with metastatic disease. However, about one-third of women with early stage breast cancer will eventually develop metastatic disease. Furthermore, approximately 20-30% of patients with breast cancer have tumors that overexpress human epidermal growth factor receptor (HER-2), which is associated with an aggressive tumor phenotype and poor prognosis. One of the treatment options islapatinib, an orally active small molecule that inhibits the tyrosine kinases of HER-2 and the epidermal growth factor receptor type 1 (EGFR). In this consensus statement current treatment options in metastatic and locally advanced disease are discussedwith a special focus on lapatinib.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

WIENER KLINISCHE WOCHENSCHRIFT

ISSN

0043-5325

e-ISSN

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Volume of the periodical

122

Issue of the periodical within the volume

11-12

Country of publishing house

AT - AUSTRIA

Number of pages

12

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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