Distribution of lipoprotein associated phospholipase A2 in Czech population and its interaction with conventional cardiovascular risk
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F13%3A%230000770" target="_blank" >RIV/00064190:_____/13:#0000770 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Distribution of lipoprotein associated phospholipase A2 in Czech population and its interaction with conventional cardiovascular risk
Original language description
INTRODUCTION: Lipoprotein associated phospholipase A2 (Lp?PLA2) represent new cardiovascular risk factor and potential treatment target. We aimed to analyze the epidemiological situation of this factor in Czech population. METHODS AND RESULTS: The studypopulation consisted from 1 962 subjects, a random samples of general population (postMONICA study), and from patients with manifest coronary or cerebrovascular disease (Czech samples of EUROASPIRE III survey). Lp?PLA2 activity was estimated using commercial kits by diaDexus Inc. in frozen samples. Increased activity (by definition, i.e. higher than195 nmol/?min/?ml) was observed in 21.1 % of sample, no apparent difference between subject with and without manifest vascular disease was found. Males showed higher Lp?PLA2 activity, than females (179.6 vs 146, resp., p less than 0.0001), while no substantial increase with age was observed. Taking Lp?PLA2 activity higher than195 as dependent variable, following independent variables entered
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Vnitřní lékařství
ISSN
0042-773X
e-ISSN
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Volume of the periodical
59
Issue of the periodical within the volume
5
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
7
Pages from-to
344-351
UT code for WoS article
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EID of the result in the Scopus database
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