Quality of Life Predictors in Chronic Stable Post-Stroke Patients and Prognostic Value of SF-36 Score as a Mortality Surrogate

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F15%3A%230001040" target="_blank" >RIV/00064190:_____/15:#0001040 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/15:10297497 RIV/00216208:11140/15:10297497 RIV/00669806:_____/15:10297497 RIV/00159816:_____/15:00068444

Result on the web

<a href="http://dx.doi.org/10.1007/s12975-015-0418-6" target="_blank" >http://dx.doi.org/10.1007/s12975-015-0418-6</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s12975-015-0418-6" target="_blank" >10.1007/s12975-015-0418-6</a>

Result language

angličtina

Original language name

Quality of Life Predictors in Chronic Stable Post-Stroke Patients and Prognostic Value of SF-36 Score as a Mortality Surrogate

Original language description

Perceived quality of life (QoL) and psychological well-being represents an important target of secondary prevention practice in post-stroke patients. We aimed to identify the major covariates of impaired QoL in stable post-stroke patients and whether impaired QoL itself represents independent mortality predictor. The study consisted of a cross-sectional and a prospective part. Three hundred forty-one patients [mean age 69.0 (SD 9.1)] were interviewed at least 6 months after discharge from hospital for their first-ever ischemic stroke. QoL was objectivized using 36-Item Short-Form Health Survey (SF-36) scoring. Standard health-related questionnaires, including Hospital Anxiety and Depression Scale (HADS), risk factors, and biochemical markers, were assessed. To estimate the 5-year all-cause and cardiovascular mortality, we ascertained the vital status and declared cause of death. Anxiety, depression (HADS score a parts per thousand yen11), brain natriuretic peptide levels a parts per thousand yen100 ng/mL, residual motor impairment at interview, Rankin Scale a parts per thousand yen4 at discharge from hospitalization, and raised blood pressure were identified as main determinants of impaired QoL in the cross-sectional part. The 5-year all-cause and cardiovascular mortality rates were 25.8 and 19.9 %, respectively. After adjustment for potential covariates, patients with an SF-36 score a parts per thousand currency sign40 at baseline had more than a twofold higher risk of all-cause and cardiovascular mortality (with HRRs 2.01 (95 % CI 1.21-3.32), p < 0.007 and 2.32 (95 % CI 1.32-4.09), p < 0.003, respectively) during the 5 years of follow-up. In conclusion, anxiety, depression, and raised brain natriuretic peptide levels were the most important covariates of impaired QoL in post-stroke patients. Moreover, a decreased SF-36 score (a parts per thousand currency sign40) represents an independent surrogate of increased additive mortality risk.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

<a href="/en/project/NT12102" target="_blank" >NT12102: Secondary prevention and prognosis of post-stroke patients</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

TRANSLATIONAL STROKE RESEARCH

ISSN

1868-4483

e-ISSN

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Volume of the periodical

6

Issue of the periodical within the volume

5

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

375-383

UT code for WoS article

000360820500007

EID of the result in the Scopus database

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