Multidrug-Resistant Tuberculosis in Europe, 2010-2011
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F15%3A%230001066" target="_blank" >RIV/00064190:_____/15:#0001066 - isvavai.cz</a>
Result on the web
<a href="http://wwwnc.cdc.gov/eid/article/21/3/14-1343_article" target="_blank" >http://wwwnc.cdc.gov/eid/article/21/3/14-1343_article</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3201/eid2103.141343" target="_blank" >10.3201/eid2103.141343</a>
Alternative languages
Result language
angličtina
Original language name
Multidrug-Resistant Tuberculosis in Europe, 2010-2011
Original language description
Drug-resistant Mycobacterium tuberculosis is challenging elimination of tuberculosis (TB). We evaluated risk factors for TB and levels of second-line drug resistance in M. tuberculosis in patients in Europe with multidrug-resistant (MDR) TB. A total of 380 patients with MDR TB and 376 patients with non-MDR TB were enrolled at 23 centers in 16 countries in Europe during 2010-2011. A total of 52.4% of MDR TB patients had never been treated for TB, which suggests primary transmission of MDR M. tuberculosis. At initiation of treatment for MDR TB, 59.7% of M. tuberculosis strains tested were resistant to pyrazinamide, 51.1% were resistant to >= 1 second-line drug, 26.6% were resistant to second-line injectable drugs, 17.6% were resistant to fluoroquinolones, and 6.8% were extensively drug resistant. Previous treatment for TB was the strongest risk factor for MDR TB. High levels of primary transmission and advanced resistance to second-line drugs characterize MDR TB cases in Europe.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FN - Epidemiology, infection diseases and clinical immunology
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
EMERGING INFECTIOUS DISEASES
ISSN
1080-6040
e-ISSN
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Volume of the periodical
21
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
409-416
UT code for WoS article
000350269300003
EID of the result in the Scopus database
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