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Controversies in antiplatelet therapy in the secondary prevention of stroke

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F16%3AN0000072" target="_blank" >RIV/00064190:_____/16:N0000072 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.eurger.2015.12.007" target="_blank" >http://dx.doi.org/10.1016/j.eurger.2015.12.007</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.eurger.2015.12.007" target="_blank" >10.1016/j.eurger.2015.12.007</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Controversies in antiplatelet therapy in the secondary prevention of stroke

  • Original language description

    Recurrence of stroke has been estimated at 3-4% yearly after TIA or stroke. There is no clear agreement in choosing antiplatelet therapy at this time. Europeans, Americans and British guidelines have been different. Aspirin is still used in secondary prevention of ischemic stroke, because of the longest experience with the best-achieved results in different studies and low price. Other used drugs are a combination of aspirin and dipyridamole, P2Y12 receptor antagonists - clopidogrel, ticlopidine, prasugrel and ticagrelor, or inhibitor of phosphodiesterase cilostazol, which was effective with Chinese and Japanese population. The common agreement is not to use a dual antiplatelet therapy in long term, because it does not carry a higher reduction of ischemic attacks than monotherapy. The other negative effect is causing more incidents with severe hemorrhage. According to the American recommendation, the combined therapy is promising early after having TIA and light stroke when the risk of recurrence of stroke is high.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    EUROPEAN GERIATRIC MEDICINE

  • ISSN

    1878-7649

  • e-ISSN

  • Volume of the periodical

    7

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    IT - ITALY

  • Number of pages

    4

  • Pages from-to

    65-69

  • UT code for WoS article

    000369751600015

  • EID of the result in the Scopus database

    2-s2.0-84958114566