A comparison of secondary prevention practice in poststroke and coronary heart disease patients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F16%3AN0000084" target="_blank" >RIV/00064190:_____/16:N0000084 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11140/16:10324849 RIV/00669806:_____/16:10324849 RIV/00216208:11110/16:10324849 RIV/00159816:_____/16:00068434

Result on the web

<a href="http://dx.doi.org/10.1016/j.puhe.2016.02.003" target="_blank" >http://dx.doi.org/10.1016/j.puhe.2016.02.003</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.puhe.2016.02.003" target="_blank" >10.1016/j.puhe.2016.02.003</a>

Result language

angličtina

Original language name

A comparison of secondary prevention practice in poststroke and coronary heart disease patients

Original language description

It is evident that patients with atherosclerotic vascular disease (AVD) benefit from appropriate secondary prevention. In clinical reality, the secondary prevention in AVD patients other than those with coronary heart disease (CHD) is often overlooked. Therefore, we compared the adherence to secondary prevention principles between poststroke and CHD patients. We examined 1729 chronic patients with AVD (mean age 65.9 (+/- SD 9.6) years), 964 with CHD, and 765 poststroke (pooled data of Czech samples of EUROASPIRE III, IV, and the ESH stroke survey). The interview was performed 6-36 months after the coronary event/revascularization or the first ischemic stroke, while the mortality follow-up 5 years after this interview. Poststroke patients had a significantly higher risk of persistent smoking, blood pressure >= 140/90 mmHg and LDL >= 2.5 mmol/L than CHD patients [odds ratios adjusted for age, gender and survey were 1.63 (95% CI: 1.13-2.33), 1.38 (95% CI: 1.13-1.69) and 2.26 (95% CI: 1.84-2.78), respectively]. In contrast, poststroke patients showed a lower risk of inappropriate glucose control and hypertriglyceridemia [0.66 (95% CI: 0.54-0.82) and 0.74 (95% CI: 0.61-0.91), respectively]. The prescription rates of antiplatelets/anticoagulants, antihypertensives and statins were also significantly lower in poststroke than in CHD patients (89.4 vs 93.7, 85.9 vs 97.5, and 57.7 vs 89.8, respectively). Mortality analysis was performed in a subsample of 815 subjects interviewed in 2006/07. The 5-year all-cause mortality rates were 25.8% and 13.3% in poststroke and coronary patients, respectively (P = 0.0023); the hazard ratio for stroke adjusted for major risk factors was 1.85 (95% CI: 1.31-2.63). Compared to CHD patients, poststroke patients are strongly handicapped in terms of poor adherence to secondary prevention target, prescription of basic pharmacotherapies and mortality risk.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

PUBLIC HEALTH

ISSN

0033-3506

e-ISSN

—

Volume of the periodical

Neuveden

Issue of the periodical within the volume

137

Country of publishing house

GB - UNITED KINGDOM

Number of pages

8

Pages from-to

64-72

UT code for WoS article

000381371400012

EID of the result in the Scopus database

2-s2.0-84961226965