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FTLD-TDP and progressive supranuclear palsy in comorbidity-a report of two cases with different clinical presentations

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F16%3AN0000221" target="_blank" >RIV/00064190:_____/16:N0000221 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/17:10359480 RIV/00216208:11120/17:43912561 RIV/00023884:_____/12:00007489 RIV/00064190:_____/17:N0000025 RIV/00064165:_____/17:10359480

  • Result on the web

    <a href="http://dx.doi.org/10.1080/13554794.2016.1264058" target="_blank" >http://dx.doi.org/10.1080/13554794.2016.1264058</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1080/13554794.2016.1264058" target="_blank" >10.1080/13554794.2016.1264058</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    FTLD-TDP and progressive supranuclear palsy in comorbidity-a report of two cases with different clinical presentations

  • Original language description

    Frontotemporal lobar degeneration with transactive response DNA-binding protein 43 (FTLD-TDP) and progressive supranuclear palsy (PSP) are distinct neurodegenerations with different clinical presentations. We report two cases with FTLD-TDP and PSP in comorbidity: a patient with amnestic dementia developing frontal lobe dementia, Parkinsonism and supranuclear gaze palsy and a patient with cerebellar ataxia and nystagmus developing akinesia, rigidity, and subcortical dementia. Neuropathological examination revealed neuronal and glial tau pathology together with ubiquitin, and phospho-TDP-43-immunoreactivities in the hippocampus, striatum, mesencephalon, and frontal and temporal cortices. Clinical and neuropathological correlations in atypical neurodegenerations are crucial to describe new entities of overlapping syndromes.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Neurocase

  • ISSN

    1355-4794

  • e-ISSN

  • Volume of the periodical

    23

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    7

  • Pages from-to

    5-11

  • UT code for WoS article

  • EID of the result in the Scopus database