Psychometric properties and minimal important differences of SF-36 in Idiopathic Pulmonary Fibrosis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F19%3AN0000075" target="_blank" >RIV/00064190:_____/19:N0000075 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/19:10396529
Result on the web
<a href="http://dx.doi.org/10.1186/s12931-019-1010-5" target="_blank" >http://dx.doi.org/10.1186/s12931-019-1010-5</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s12931-019-1010-5" target="_blank" >10.1186/s12931-019-1010-5</a>
Alternative languages
Result language
angličtina
Original language name
Psychometric properties and minimal important differences of SF-36 in Idiopathic Pulmonary Fibrosis
Original language description
BackgroundIdiopathic pulmonary fibrosis (IPF) is a rare disease with a median survival of 3-5years after diagnosis with limited treatment options. The aim of this study is to assess the psychometric characteristics of the Short Form 36 Health Status Questionnaire (SF-36) in IPF and to provide disease specific minimally important differences (MID).MethodsData source was the European IPF Registry (eurIPFreg). The psychometric properties of the SF-36 version 2 were evaluated based on objective clinical measures as well as subjective perception. We analysed acceptance, feasibility, discrimination ability, construct and criterion validity, responsiveness and test-retest-reliability. MIDs were estimated via distribution and anchor-based approaches.ResultsThe study population included 258 individuals (73.3% male; mean age 67.3years, SD 10.7). Of them 75.2% (194 individuals) had no missing item. The distribution of several items was skewed, although floor effect was acceptable. Physical component score (PCS) correlated significantly and moderately with several anchors, whereas the correlations of mental component score (MCS) and anchors were only small. The tests showed mainly significant lower HRQL in individuals with long-term oxygen therapy. Analyses in stable individuals did not show significant changes of HRQL except for one dimension and anchor. Individuals with relevant changes of the health status based on the anchors had significant changes in all SF-36 dimensions and summary scales except for the dimension PAIN. PCS and MCS had mean MIDs of five and six, respectively. Mean MIDs of the dimensions ranged from seven to 21.ConclusionIt seems that the SF-36 is a valid instrument to measure HRQL in IPF and so can be used in RCTs or individual monitoring of disease. Nevertheless, the additional evaluation of longitudinal aspects and MIDs can be recommended to further analyse these factors. Our findings have a great potential impact on the evaluation of IPF patients.Trial registrationThe eurIPFreg and eurIPFbank are listed in https://clinicaltrials.gov (NCT02951416).
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30203 - Respiratory systems
Result continuities
Project
—
Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
RESPIRATORY RESEARCH
ISSN
1465-993X
e-ISSN
1465-9921
Volume of the periodical
20
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
11
Pages from-to
Article Number: 47
UT code for WoS article
000460213400001
EID of the result in the Scopus database
2-s2.0-85064504556