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Cancer detection rates and inter-examiner variability of MRI/TRUS fusion targeted biopsy and systematic transrectal biopsy

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F19%3AN0000130" target="_blank" >RIV/00064190:_____/19:N0000130 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/20:10414590 RIV/00216208:11120/20:43920523 RIV/00216208:11130/20:10414590 RIV/00064203:_____/20:10414590 RIV/00064190:_____/20:N0000044

  • Result on the web

    <a href="https://biomed.papers.upol.cz/getrevsrc.php?identification=public&mag=bio&raid=2137&type=fin&ver=3" target="_blank" >https://biomed.papers.upol.cz/getrevsrc.php?identification=public&mag=bio&raid=2137&type=fin&ver=3</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.5507/bp.2019.050" target="_blank" >10.5507/bp.2019.050</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Cancer detection rates and inter-examiner variability of MRI/TRUS fusion targeted biopsy and systematic transrectal biopsy

  • Original language description

    Background: Software-based MRI/TRUS fusion biopsy depends on the coordination of several steps, and inter-examiner differences could influence the results. The aim of this bicentric prospective study was to compare the detection rates of MRI/TRUS fusion targeted biopsy (TG) and systematic biopsy (SB), and the detection rates of examiners with different levels of previous experience in prostate biopsy. Methods: A total of 419 patients underwent MRI based on a suspicion of prostate cancer with elevated PSA levels. MRI was positive in 395 patients (221 in the first biopsy group [FB] and 174 in the repeated biopsy group [RB]). A subsequent TG, followed by a SB, was performed on these patients by four different examiners. Results: In the detection of clinically significant prostate cancer, a significant difference was found for TG+SB against SB in the RB group (35.1% vs. 25.3%, P=0.047). In the detection of clinically insignificant prostate cancer, the SB had a significantly higher detection rate than TG in both subgroups (FB: 11.9% vs. 4.7%, P=0.008; RB: 13.8% vs. 6.9%, P=0.034). A significant difference was found between the four examiners in the FB for TG (P=0.028), SB (P=0.036), and TG+SB (P=0.017). Conclusion: MRI/TRUS TG in combination with SB had significantly higher detection rates than SB in the RB group only. Differences in detection rates between examiners were dependent on the level of previous experience with TRUS guided biopsy.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>ost</sub> - Miscellaneous article in a specialist periodical

  • CEP classification

  • OECD FORD branch

    30204 - Oncology

Result continuities

  • Project

    <a href="/en/project/NV15-27047A" target="_blank" >NV15-27047A: Use of MRI with transrectal ultrasonography fusion for detecting prostate cancer</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia

  • ISSN

    1213-8118

  • e-ISSN

  • Volume of the periodical

    neuveden

  • Issue of the periodical within the volume

    10/2019 online

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    6

  • Pages from-to

    nestránkovano

  • UT code for WoS article

  • EID of the result in the Scopus database