Ten Years' Experience with the Discontinuation of the Bacillus Calmette-Guerin Vaccination in the Czech Republic

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F21%3AN0000070" target="_blank" >RIV/00064190:_____/21:N0000070 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/21:10428931 RIV/00216208:11130/21:10428931

Result on the web

<a href="http://dx.doi.org/10.4103/ijmy.ijmy_85_21" target="_blank" >http://dx.doi.org/10.4103/ijmy.ijmy_85_21</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4103/ijmy.ijmy_85_21" target="_blank" >10.4103/ijmy.ijmy_85_21</a>

Result language

angličtina

Original language name

Ten Years' Experience with the Discontinuation of the Bacillus Calmette-Guerin Vaccination in the Czech Republic

Original language description

Background: Bacillus Calmette-Guerin (BCG) vaccination programs were introduced in Czechoslovakia more than 60 years ago under a quite different epidemiological situation than that of today. Compulsory mass BCG vaccination was abolished in November 2010 and changed to a selective vaccination program for infants at high risk of contracting tuberculosis (TB). Methods: This work sets out to ascertain the risk of TB and nontuberculous mycobacterial (NTM) infection in the 10-year period following the change to the vaccination program and to compare this with the same period of time when mass BCG vaccination was compulsory. Descriptive study. Statistical analysis of the incidence of tuberculosis and non-tuberculous mycobacteriosis as reported in the TB register in years 2001-2020. Conclusions: The incidence trend of TB in children in both monitored time periods is identical and statistically significantly decreasing (P < 0.001). In the first monitored period, the incidence trend of NTM cervical lymphadenitis in children is degressive and is not statistically significant (P = 0.561). However, in the second monitored period, the trend increases and is statistically significant (P < 0.001); in every compared 2-consecutive year period, there is an increase of 8%. These findings indicate that the change from mass BCG vaccination to selective vaccination of high-risk newborns and the abolishment of BCG revaccination can be recommended, so long as a keen eye is kept on NTM caused lymphadenitis.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30303 - Infectious Diseases

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

INTERNATIONAL JOURNAL OF MYCOBACTERIOLOGY

ISSN

2212-5531

e-ISSN

2212-554X

Volume of the periodical

10

Issue of the periodical within the volume

2

Country of publishing house

IN - INDIA

Number of pages

6

Pages from-to

193-198

UT code for WoS article

000668753800015

EID of the result in the Scopus database

2-s2.0-85108649596