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The prognostic impact of renal function decline during hospitalization for myocardial infarction

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F21%3AN0000095" target="_blank" >RIV/00064190:_____/21:N0000095 - isvavai.cz</a>

  • Alternative codes found

    RIV/00669806:_____/21:10423757 RIV/00216208:11140/21:10423757

  • Result on the web

    <a href="http://dx.doi.org/10.2217/cer-2020-0085" target="_blank" >http://dx.doi.org/10.2217/cer-2020-0085</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.2217/cer-2020-0085" target="_blank" >10.2217/cer-2020-0085</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The prognostic impact of renal function decline during hospitalization for myocardial infarction

  • Original language description

    Aim: We analyzed the mortality risk of myocardial infarction (MI) patients according to renal function, observed during hospitalization. Materials & methods: Patients hospitalized for MI between 2006 and 2018 were followed (n = 5659). We divided the sample into four groups by estimated glomerular filtration (eGFR) [ml/min]: normal functions (lowest eGFR during hospitalization >60); transiently moderate insufficiency (lowest eGFR >30 and <= 60, highest >60); permanently moderate insufficiency (highest eGFR >30 and <= 60); severe insufficiency (highest and lowest eGFR <= 30). Results: Permanently moderate renal insufficiency indicates increased 5-years all-cause mortality (hazard risk ratio: 2.27 [95% CIs: 1.87-2.75], p < 0.0001), but a similar risk was found in patients with the only transient decline of renal functions (hazard risk ratio: 2.08 [95% CIs: 1.70-2.55], p < 0.0001). Both moderate insufficiency subgroups (transient/permanent) did not statistically differ regarding mortality risk. Conclusion: Even just fluctuation of eGFR toward moderate insufficiency during hospitalization represents an important prognostic indicator in MI patients.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30201 - Cardiac and Cardiovascular systems

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH

  • ISSN

    2042-6305

  • e-ISSN

    2042-6313

  • Volume of the periodical

    10

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    11

  • Pages from-to

    219-228

  • UT code for WoS article

    000614756900001

  • EID of the result in the Scopus database

    2-s2.0-85101127880