Prevalence of SARS-COV-2 antibodies in the Thomayer University Hospital staff after the first wave of COVID-19

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F22%3AN0000001" target="_blank" >RIV/00064190:_____/22:N0000001 - isvavai.cz</a>

Result on the web

<a href="https://www.prolekare.cz/en/journals/epidemiology-microbiology-immunology/2022-1-21/prevalence-of-sars-cov-2-antibodies-in-the-thomayer-university-hospital-staff-after-the-first-wave-of-covid-19-130625?hl=en" target="_blank" >https://www.prolekare.cz/en/journals/epidemiology-microbiology-immunology/2022-1-21/prevalence-of-sars-cov-2-antibodies-in-the-thomayer-university-hospital-staff-after-the-first-wave-of-covid-19-130625?hl=en</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Prevalence of SARS-COV-2 antibodies in the Thomayer University Hospital staff after the first wave of COVID-19

Original language description

Objectives: To map the prevalence of SARS-CoV-2 antibodies in the staff of the Thomayer University Hospital in Prague following the first wave of COVID-19. The main reason was the large number of COVID-19 patients admitted to the Thomayer University Hospital with confirmed SARS-CoV-2 infection. Material and Methods: A volunteer study based on a questionnaire survey and determination of total antibodies (ECLIA, Roche) and individual classes of immunoglobulins (ELISA IgG and IgA, Euroimmun). Results: The study involved 808 employees, 2/3 of whom were from clinical departments. Fifteen participants, predominantly nurses (n = 12), tested ECLIA positive for antibodies against SARS-CoV-2 and ELISA positive or borderline positive for IgG antibodies. Positive or borderline IgA antibodies were recorded in 12 subjects. Most of the positive study participants (n = 13) contracted the SARS-CoV-2 virus at the workplace after repeated contact with positive patients. Most subjects infected (n = 12) had a more severe course but did not require hospitalization. We detected only one asymptomatic antibody-positive person. Conclusions: After the first wave of COVID-19, SARS-CoV-2 antibodies were only demonstrated in 1.9% of the Thomayer University Hospital employees tested. In clinical departments, the positivity rate was 2.3%, and in non-clinical departments, it was only 0.5%. The low prevalence of antibodies points to the low number of infected hospital staff and a very good level of compliance with all public health and epidemiological measures.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30102 - Immunology

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

EPIDEMIOLOGIE MIKROBIOLOGIE IMUNOLOGIE

ISSN

1210-7913

e-ISSN

1805-451X

Volume of the periodical

71

Issue of the periodical within the volume

1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

3-8

UT code for WoS article

000829254900001

EID of the result in the Scopus database

2-s2.0-85128956194