Invasive measurement of hepatic venous pressure gradient before resection of hepatocellular carcinoma

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F23%3A10001084" target="_blank" >RIV/00064190:_____/23:10001084 - isvavai.cz</a>

Alternative codes found

RIV/60162694:G44__/24:00563062 RIV/61383082:_____/23:00001282 RIV/00216208:11130/23:10475460 RIV/00216208:11110/23:10475460

Result on the web

<a href="https://www.termedia.pl/Invasive-measurement-of-hepatic-venous-pressure-gradient-before-resection-of-hepatocellular-carcinoma,80,51287,1,1.html" target="_blank" >https://www.termedia.pl/Invasive-measurement-of-hepatic-venous-pressure-gradient-before-resection-of-hepatocellular-carcinoma,80,51287,1,1.html</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5114/ceh.2023.130662" target="_blank" >10.5114/ceh.2023.130662</a>

Result language

angličtina

Original language name

Invasive measurement of hepatic venous pressure gradient before resection of hepatocellular carcinoma

Original language description

Aim of the study: To evaluate the role of hepatic venous pressure gradient (HVPG) measurement in patients with resectable hepatocellular carcinoma (HCC) we describe our experience with the procedure as part of our hospital standard preoperative algorithm. We present our protocol for this situation, the HVPG measurement procedure, and the results of our cohort. Material and methods: We performed a retrospective statistical analysis of all patients who underwent planned hepatic resection for HCC with HVPG measurement between 1/2016 and 1/2023. The cohort included 35 patients (30 males, mean age 69.5 years) who underwent HVPG measurement before liver resection for HCC. Results: The success rate of measurement was 91.4%, with serious complications in 2.9% of cases. Due to the clinically significant portal hypertension (CSPH) 31.3% of patients were rejected for resection. Seventeen patients with excluded CSPH underwent resection with one case of a postoperative liver event, liver decompensation, representing 5.9% of them. One patient (5.9%) had a complicated postoperative course with fasciitis. None of the patients who underwent resection (88.2%) was readmitted to the hospital due to surgical complications or a liver event during 90 days of follow-up, and no death was reported. The median overall survival (OS) in the resected subgroup was 70 months (95% CI: 52-86), and in patients rejected for surgery (resection and transplantation) 35 months (95% CI: 13-48). Conclusions: HVPG measurement is the gold standard for the quantification of portal hypertension. Hepatic vein catheterization is invasive, but a safe procedure, with a clear impact on the management of resectable HCC. (C) 2023 Termedia Publishing House Ltd.. All rights reserved.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30204 - Oncology

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Clinical and Experimental Hepatology

ISSN

2392-1099

e-ISSN

2449-8238

Volume of the periodical

9

Issue of the periodical within the volume

3

Country of publishing house

PL - POLAND

Number of pages

7

Pages from-to

236-242

UT code for WoS article

001153293000007

EID of the result in the Scopus database

2-s2.0-85174188578