Strict Blood-Pressure Control and Progression of Renal Failure in Children

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F09%3A5336" target="_blank" >RIV/00064203:_____/09:5336 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/09:5336
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Strict Blood-Pressure Control and Progression of Renal Failure in Children
Original language description
The blood-pressure target for optimal renal protection is controversial. After a 6-month run-in period, 385 children, 3 to 18 years of age, with glomerular filtration rate of 15 to 80 ml per minute per 1.73 m(2) of BSA received ramipril at a dose of 6 mgper square meter of BSA per day. Patients were randomly assigned to intensified blood-pressure control (with a target 24-hour mean arterial pressure below the 50th percentile) or conventional blood-pressure control (mean arterial pressure in the 50th to95th percentile), achieved by the addition of antihypertensive therapy; patients were followed for 5 years. Intensified blood-pressure control, with target 24-hour blood-pressure levels in the low range of normal, confers a substantial benefit with respect to renal function among children with chronic kidney disease.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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