Reactivity to Helicobacter pylori Antigens in Patients Suffering from Thyroid Gland Autoimmunity

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F09%3A5419" target="_blank" >RIV/00064203:_____/09:5419 - isvavai.cz</a>

Alternative codes found

RIV/00669806:_____/09:00202615 RIV/00216208:11130/09:5419 RIV/00216208:11140/09:00202110

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Reactivity to Helicobacter pylori Antigens in Patients Suffering from Thyroid Gland Autoimmunity

Original language description

In this study we concentrated on relationship between Helicobacter pylori and autoimmune thyroiditis. Forty seven AT patients and 34 healthy controls were enrolled. Study subjects were split according to Helicobacter pylori positivity. Their peripheral blood mononuclear cells were stimulated by H.pylori lysate and its lipopolysacharide (LPS) and cytokine production was studied. We observed different "reactivity pattern" to H. pylori within groups with low basal cytokine and chemokine production in healthy H.pylori negative controls but with clear specific response in IFN-gamma and TGF-beta production in this group. Adequate immune reaction which is joined to appropriate immunoregulation leads to prevention of the chronic infection and on the other handmay prevent the development of "connected" diseases such as autoimmune.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

—

Project

<a href="/en/project/NR8887" target="_blank" >NR8887: Autoimmune thyroiditis in children and the role of simultaneous Helicobacter pylori infection</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Experimental and Clinical Endocrinology & Diabetes

ISSN

0947-7349

e-ISSN

—

Volume of the periodical

117

Issue of the periodical within the volume

8

Country of publishing house

DE - GERMANY

Number of pages

9

Pages from-to

—

UT code for WoS article

000270680100011

EID of the result in the Scopus database

—