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ČeštinaEnglish

Fractionated Plasma Separation and Adsorption Significantly Decreases Intracranial Pressure in Acute Liver Failure: Experimental Study

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F09%3A5468" target="_blank" >RIV/00064203:_____/09:5468 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11130/09:5468

  • Result on the web

    —

  • DOI - Digital Object Identifier

    —

Alternative languages

  • Result language

    angličtina

  • Original language name

    Fractionated Plasma Separation and Adsorption Significantly Decreases Intracranial Pressure in Acute Liver Failure: Experimental Study

  • Original language description

    The aim of the study was to determine the influence of fractionated plasma separation and absorption (FPSA) on intracranial pressure (ICP) in acute liver failure (ALF). METHODS: A surgical model of ALF in pigs (35-40 kg) was used. We compared laboratorydata and haemodynamic parameters from the ALF control group to the ALF group treated by Prometheus using ANOVA with repeated measures and grouping factors, by calculating the area under the curve, and by the Mann-Whitney rank test. RESULTS: Bilirubin levels differed significantly in favour of the FPSA treatment group. ICP values differed significantly in favour of the FPSA treatment group.The authors demonstrated that a significant decrease in ICP was found in pigs with ALF following treatment by FPSA.

  • Czech name

    —

  • Czech description

    —

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FJ - Surgery including transplantology

  • OECD FORD branch

    —

Result continuities

  • Project

    <a href="/en/project/OVUVN200800002" target="_blank" >OVUVN200800002: Non biological supportive therapy in heavy liver trauma in experiment</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    European surgical research

  • ISSN

    0014-312X

  • e-ISSN

    —

  • Volume of the periodical

    42

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    6

  • Pages from-to

    —

  • UT code for WoS article

    000265131400005

  • EID of the result in the Scopus database

    —

Similar results(10)

Cerebral microdialysis reflects the neuroprotective effect of fractionated plasma separation and adsorption in acute liver failure better and earlier than intracranial pressure: a controlled study in pigsFinal report of the project Biological and non-Biological elimination methodes in a treatment of acute liver failure in the experimentBiological and non-biological elimination therapy of acute liver failure. Experimental study on large laboratory animal.